Our research involves applying mass spectrometry-based technologies to perform molecular phenotyping at the population level. This work entails the development of both LC/MS and GC/MS methods for the quantification of lipids and other metabolites. A major focus of the lab also centers on developing the associated bioinformatics approaches including pathway analysis and network construction as well as multivariate statistical methods for integration of 'omics-based data structures.
Lab news
KI News
PubMed
- Role of Hippo/ACSL4 axis in ferroptosis-induced pericyte loss and vascular dysfunction in sepsis
- Serum metabolomic profiling of incident type 2 diabetes mellitus in the Multi-Ethnic Study of Atherosclerosis and Rotterdam Study
- Investigation of the effectiveness and molecular mechanisms of thiamin priming to control early blight disease in potato
- Structure of the human TSC:WIPI3 lysosomal recruitment complex
- Protein phosphatase 1 catalytic subunit gamma is a causative gene for meat lightness and redness
VR News
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- MATRAC 1 School - time to apply
- Decision within Conference grants
- Open call - JPIAMR Network Call on Virtual Research Institute
Metabolomics News
- Cmbio Launches to Provide a Centralized Hub for Microbiome and Metabolomics Services - Genetic Engineering & Biotechnology News
- Sevoflurane exposure in early life: mitochondrial dysfunction and neurotoxicity in immature rat brains without long-term memory loss - Nature.com
- Jetlag Impacts Our Metabolism, but to a Lesser Extent Than Sleepiness - Technology Networks
- Implementation of multi-omics in diagnosis of pediatric rare diseases - Nature.com
- Evaluation of Extraction Solvents for Untargeted Metabolomics to decipher the Dissolved Organic Matter of Antarctic Cryoconite Holes - Astrobiology News