Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

Metabolome-Wide Reprogramming Modulated by Wnt/β-Catenin Signaling Pathway

Wed, 07/12/2022 - 12:00
J Microbiol Biotechnol. 2022 Nov 18;33(1):1-9. doi: 10.4014/jmb.2211.11013. Online ahead of print.NO ABSTRACTPMID:36474320 | DOI:10.4014/jmb.2211.11013

The sex-specific metabolic signature of C57BL/6NRj mice during aging

Tue, 06/12/2022 - 12:00
Sci Rep. 2022 Dec 6;12(1):21050. doi: 10.1038/s41598-022-25396-8.NO ABSTRACTPMID:36473898 | DOI:10.1038/s41598-022-25396-8

<sup>1</sup>H NMR metabolomics analysis of oil palm stem tissue infected by Ganoderma boninense based on field severity Indices

Tue, 06/12/2022 - 12:00
Sci Rep. 2022 Dec 6;12(1):21087. doi: 10.1038/s41598-022-25450-5.NO ABSTRACTPMID:36473892 | DOI:10.1038/s41598-022-25450-5

Metabolic Profiling of <em>Oryza sativa</em> L. Triggered by Chilling Stress Using Ultraperformance Liquid Chromatography Coupled with Quadrupole/Time-of-Flight Mass Spectrometry (UPLC-QTOF-MS) with Transcriptome Analysis

Tue, 06/12/2022 - 12:00
J Agric Food Chem. 2022 Dec 6. doi: 10.1021/acs.jafc.2c05949. Online ahead of print.NO ABSTRACTPMID:36473722 | DOI:10.1021/acs.jafc.2c05949

Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats

Tue, 06/12/2022 - 12:00
J Ethnopharmacol. 2022 Dec 3:116007. doi: 10.1016/j.jep.2022.116007. Online ahead of print.NO ABSTRACTPMID:36473618 | DOI:10.1016/j.jep.2022.116007

Integrated analysis of transcriptomics and metabolomics in human hepatocellular carcinoma HepG2215 cells after YAP1 knockdown

Tue, 06/12/2022 - 12:00
Acta Histochem. 2022 Dec 3;125(1):151987. doi: 10.1016/j.acthis.2022.151987. Online ahead of print.NO ABSTRACTPMID:36473310 | DOI:10.1016/j.acthis.2022.151987

A simple LC-MS/MS method for the simultaneous quantification of drug metabolic enzymes

Tue, 06/12/2022 - 12:00
J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Nov 29;1214:123536. doi: 10.1016/j.jchromb.2022.123536. Online ahead of print.NO ABSTRACTPMID:36473299 | DOI:10.1016/j.jchromb.2022.123536

CCS Predictor 2.0: An Open-Source Jupyter Notebook Tool for Filtering Out False Positives in Metabolomics

Tue, 06/12/2022 - 12:00
Anal Chem. 2022 Dec 6. doi: 10.1021/acs.analchem.2c03491. Online ahead of print.NO ABSTRACTPMID:36473057 | DOI:10.1021/acs.analchem.2c03491

Chromoplast plastoglobules recruit the carotenoid biosynthetic pathway and contribute to carotenoid accumulation during tomato fruit maturation

Tue, 06/12/2022 - 12:00
PLoS One. 2022 Dec 6;17(12):e0277774. doi: 10.1371/journal.pone.0277774. eCollection 2022.NO ABSTRACTPMID:36472971 | DOI:10.1371/journal.pone.0277774

Integrating ion mobility into comprehensive multidimensional metabolomics workflows: critical considerations

Tue, 06/12/2022 - 12:00
Metabolomics. 2022 Dec 6;18(12):104. doi: 10.1007/s11306-022-01961-0.NO ABSTRACTPMID:36472678 | DOI:10.1007/s11306-022-01961-0

Serum neurofilament light chain: a novel biomarker for early diabetic sensorimotor polyneuropathy

Tue, 06/12/2022 - 12:00
Diabetologia. 2022 Dec 6. doi: 10.1007/s00125-022-05846-8. Online ahead of print.NO ABSTRACTPMID:36472640 | DOI:10.1007/s00125-022-05846-8

Metabolic Promiscuity of an Orphan Small Alarmone Hydrolase Facilitates Bacterial Environmental Adaptation

Tue, 06/12/2022 - 12:00
mBio. 2022 Dec 6:e0242222. doi: 10.1128/mbio.02422-22. Online ahead of print.NO ABSTRACTPMID:36472432 | DOI:10.1128/mbio.02422-22

Horizontal Transfer of Bacteriocin Biosynthesis Genes Requires Metabolic Adaptation To Improve Compound Production and Cellular Fitness

Tue, 06/12/2022 - 12:00
Microbiol Spectr. 2022 Dec 6:e0317622. doi: 10.1128/spectrum.03176-22. Online ahead of print.NO ABSTRACTPMID:36472430 | DOI:10.1128/spectrum.03176-22

Metabolomics and Transcriptomics Analyses Reveal Regulatory Networks Associated with Fatty Acid Accumulation in Pecan Kernels

Tue, 06/12/2022 - 12:00
J Agric Food Chem. 2022 Dec 6. doi: 10.1021/acs.jafc.2c06947. Online ahead of print.NO ABSTRACTPMID:36472227 | DOI:10.1021/acs.jafc.2c06947

Novel Method for Comprehensive Annotation of Plant Glycosides Based on Untargeted LC-HRMS/MS Metabolomics

Tue, 06/12/2022 - 12:00
Anal Chem. 2022 Dec 6;94(48):16604-16613. doi: 10.1021/acs.analchem.2c02362. Epub 2022 Nov 23.NO ABSTRACTPMID:36472119 | DOI:10.1021/acs.analchem.2c02362

Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics

Tue, 06/12/2022 - 12:00
Zhongguo Zhong Yao Za Zhi. 2022 Oct;47(19):5224-5234. doi: 10.19540/j.cnki.cjcmm.20220128.303.NO ABSTRACTPMID:36472029 | DOI:10.19540/j.cnki.cjcmm.20220128.303

Mechanism of pathogenesis of Jingfang Mixture in intervention of chronic spontaneous urticaria based on serum metabolomics

Tue, 06/12/2022 - 12:00
Zhongguo Zhong Yao Za Zhi. 2022 Oct;47(20):5488-5493. doi: 10.19540/j.cnki.cjcmm.20220610.401.NO ABSTRACTPMID:36471964 | DOI:10.19540/j.cnki.cjcmm.20220610.401

Compatibility mechanism of Trichosanthis Fructus-Allii Macrostemonis Bulbus combination against atherosclerosis: based on metabolomics and network pharmacology

Tue, 06/12/2022 - 12:00
Zhongguo Zhong Yao Za Zhi. 2022 Nov;47(22):6207-6216. doi: 10.19540/j.cnki.cjcmm.20220727.701.NO ABSTRACTPMID:36471946 | DOI:10.19540/j.cnki.cjcmm.20220727.701

Mechanism of Cyathulae Radix in treatment of knee osteoarthritis based on metabolomics

Tue, 06/12/2022 - 12:00
Zhongguo Zhong Yao Za Zhi. 2022 Nov;47(22):6199-6206. doi: 10.19540/j.cnki.cjcmm.20220706.703.NO ABSTRACTPMID:36471945 | DOI:10.19540/j.cnki.cjcmm.20220706.703

Biomarkers related to cognitive dysfunction in APP/PS1 mice based on non-targeted metabonomics and intervention mechanism of Huanglian Jiedu Decoction

Tue, 06/12/2022 - 12:00
Zhongguo Zhong Yao Za Zhi. 2022 Nov;47(22):6117-6126. doi: 10.19540/j.cnki.cjcmm.20220705.401.NO ABSTRACTPMID:36471936 | DOI:10.19540/j.cnki.cjcmm.20220705.401

Pages