Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

The alteration of urinary metabolomics profiles in Kashin-Beck disease in a three consecutive year study

Mon, 12/12/2022 - 12:00
Mol Omics. 2022 Dec 12. doi: 10.1039/d2mo00297c. Online ahead of print.NO ABSTRACTPMID:36508252 | DOI:10.1039/d2mo00297c

Radiation therapy induces innate immune responses in patients treated for prostate cancers

Mon, 12/12/2022 - 12:00
Clin Cancer Res. 2022 Dec 12:CCR-22-2340. doi: 10.1158/1078-0432.CCR-22-2340. Online ahead of print.NO ABSTRACTPMID:36508164 | DOI:10.1158/1078-0432.CCR-22-2340

Diabetes Retinopathy: New Ways to Detect and Treat

Mon, 12/12/2022 - 12:00
Methods Mol Biol. 2023;2592:89-100. doi: 10.1007/978-1-0716-2807-2_6.NO ABSTRACTPMID:36507987 | DOI:10.1007/978-1-0716-2807-2_6

Deciphering the Role of <em>Klf10</em> in the Cerebellum

Mon, 12/12/2022 - 12:00
J Biomed Sci Eng. 2022 May;15(5):140-156. doi: 10.4236/jbise.2022.155014. Epub 2022 May 30.NO ABSTRACTPMID:36507464 | PMC:PMC9733405 | DOI:10.4236/jbise.2022.155014

Identification of key genes controlling soluble sugar and glucosinolate biosynthesis in Chinese cabbage by integrating metabolome and genome-wide transcriptome analysis

Mon, 12/12/2022 - 12:00
Front Plant Sci. 2022 Nov 25;13:1043489. doi: 10.3389/fpls.2022.1043489. eCollection 2022.NO ABSTRACTPMID:36507456 | PMC:PMC9732556 | DOI:10.3389/fpls.2022.1043489

Combined physiological and metabolomic analysis reveals the effects of different biostimulants on maize production and reproduction

Mon, 12/12/2022 - 12:00
Front Plant Sci. 2022 Nov 23;13:1062603. doi: 10.3389/fpls.2022.1062603. eCollection 2022.NO ABSTRACTPMID:36507449 | PMC:PMC9727306 | DOI:10.3389/fpls.2022.1062603

Dynamic regulation of phenylpropanoid pathway metabolites in modulating sorghum defense against fall armyworm

Mon, 12/12/2022 - 12:00
Front Plant Sci. 2022 Nov 25;13:1019266. doi: 10.3389/fpls.2022.1019266. eCollection 2022.NO ABSTRACTPMID:36507437 | PMC:PMC9732255 | DOI:10.3389/fpls.2022.1019266

Corrigendum: Integrated metabolomics and transcriptomics insights on flavonoid biosynthesis of a medicinal functional forage, <em>Agriophyllum squarrosum</em> (L.), based on a common garden trial covering six ecotypes

Mon, 12/12/2022 - 12:00
Front Plant Sci. 2022 Nov 23;13:1092707. doi: 10.3389/fpls.2022.1092707. eCollection 2022.NO ABSTRACTPMID:36507418 | PMC:PMC9727375 | DOI:10.3389/fpls.2022.1092707

Comparative metabolomics provides novel insights into correlation between dominant habitat factors and constituents of <em>Stellaria Radix</em> (<em>Stellaria dichotoma</em> L. var. <em>lanceolata</em> Bge.)

Mon, 12/12/2022 - 12:00
Front Plant Sci. 2022 Nov 25;13:1035712. doi: 10.3389/fpls.2022.1035712. eCollection 2022.NO ABSTRACTPMID:36507406 | PMC:PMC9733579 | DOI:10.3389/fpls.2022.1035712

Multi-omics analysis reveals GABAergic dysfunction after traumatic brainstem injury in rats

Mon, 12/12/2022 - 12:00
Front Neurosci. 2022 Nov 23;16:1003300. doi: 10.3389/fnins.2022.1003300. eCollection 2022.NO ABSTRACTPMID:36507346 | PMC:PMC9726735 | DOI:10.3389/fnins.2022.1003300

Integrated transcriptomic and metabolomic profiling reveals dysregulation of purine metabolism during the acute phase of spinal cord injury in rats

Mon, 12/12/2022 - 12:00
Front Neurosci. 2022 Nov 23;16:1066528. doi: 10.3389/fnins.2022.1066528. eCollection 2022.NO ABSTRACTPMID:36507345 | PMC:PMC9727392 | DOI:10.3389/fnins.2022.1066528

A multi-omics based anti-inflammatory immune signature characterizes Long COVID Syndrome

Mon, 12/12/2022 - 12:00
iScience. 2022 Dec 5:105717. doi: 10.1016/j.isci.2022.105717. Online ahead of print.NO ABSTRACTPMID:36507225 | PMC:PMC9719844 | DOI:10.1016/j.isci.2022.105717

Effects of Gabexate Mesylate on the Gut Microbiota and Metabolomics in Rats with Sepsis

Mon, 12/12/2022 - 12:00
J Inflamm Res. 2022 Dec 5;15:6581-6594. doi: 10.2147/JIR.S392060. eCollection 2022.NO ABSTRACTPMID:36506782 | PMC:PMC9733569 | DOI:10.2147/JIR.S392060

Stage related metabolic profile of the synovial fluid in patients with acute flares of knee osteoarthritis

Mon, 12/12/2022 - 12:00
Med Pharm Rep. 2022 Oct;95(4):438-445. doi: 10.15386/mpr-2454. Epub 2022 Oct 27.NO ABSTRACTPMID:36506601 | PMC:PMC9694744 | DOI:10.15386/mpr-2454

Metabolomics profiling of AKT/c-Met-induced hepatocellular carcinogenesis and the inhibitory effect of Cucurbitacin B in mice

Mon, 12/12/2022 - 12:00
Front Pharmacol. 2022 Nov 23;13:1009767. doi: 10.3389/fphar.2022.1009767. eCollection 2022.NO ABSTRACTPMID:36506561 | PMC:PMC9728611 | DOI:10.3389/fphar.2022.1009767

Comparative metabolic profiling of wild <em>Cordyceps</em> species and their substituents by liquid chromatography-tandem mass spectrometry

Mon, 12/12/2022 - 12:00
Front Pharmacol. 2022 Nov 24;13:1036589. doi: 10.3389/fphar.2022.1036589. eCollection 2022.NO ABSTRACTPMID:36506548 | PMC:PMC9729555 | DOI:10.3389/fphar.2022.1036589

Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics

Mon, 12/12/2022 - 12:00
Front Pharmacol. 2022 Nov 23;13:1066244. doi: 10.3389/fphar.2022.1066244. eCollection 2022.NO ABSTRACTPMID:36506541 | PMC:PMC9727497 | DOI:10.3389/fphar.2022.1066244

Discovery of the key active compounds in Citri Reticulatae Pericarpium (<em>Citrus reticulata</em> "Chachi") and their therapeutic potential for the treatment of COVID-19 based on comparative metabolomics and network pharmacology

Mon, 12/12/2022 - 12:00
Front Pharmacol. 2022 Nov 23;13:1048926. doi: 10.3389/fphar.2022.1048926. eCollection 2022.NO ABSTRACTPMID:36506534 | PMC:PMC9727096 | DOI:10.3389/fphar.2022.1048926

Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury

Mon, 12/12/2022 - 12:00
Front Pharmacol. 2022 Nov 23;13:1043945. doi: 10.3389/fphar.2022.1043945. eCollection 2022.NO ABSTRACTPMID:36506525 | PMC:PMC9727196 | DOI:10.3389/fphar.2022.1043945

Serum and brain metabolomic study reveals the protective effects of Bai-Mi-Decoction on rats with ischemic stroke

Mon, 12/12/2022 - 12:00
Front Pharmacol. 2022 Nov 24;13:1005301. doi: 10.3389/fphar.2022.1005301. eCollection 2022.NO ABSTRACTPMID:36506507 | PMC:PMC9729534 | DOI:10.3389/fphar.2022.1005301

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