Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

Metabolomics News

PLOS Biology is Experimental Biology - PLoS Blogs (blog)

Sat, 02/04/2016 - 04:59
PLOS Biology is Experimental BiologyPLoS Blogs (blog)In this study, the authors investigate how the antidiabetic drug metformin inhibits cancer. Using metabolomics they find that metformin blocks tumor cell proliferation independently of the classic metabolic checkpoints by suppressing mitochondrial ...

Living off the fat of the land - Washington University in St. Louis Newsroom

Fri, 01/04/2016 - 17:45
Washington University in St. Louis NewsroomLiving off the fat of the landWashington University in St. Louis Newsroom“It has only been possible to think about glucose metabolism at the systems level for the past few years,” Patti said, referring to the new discipline of metabolomics. “Before that, the technology to follow glucose through all the possible metabolic ...

A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR - Nature.com

Fri, 01/04/2016 - 09:00
A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR  Nature.comWe previously reported that the combination of two safe proteostasis regulators, cysteamine and epigallocatechin gallate (EGCG), can be used to improve ...

A Different Way of Doing Things - The Scientist

Fri, 01/04/2016 - 06:07
The ScientistA Different Way of Doing ThingsThe ScientistUsing forward genetics and metabolomics approaches, our group4 and Matt Vander Heiden's lab at MIT5 recently demonstrated that aspartate levels decrease dramatically when respiration is blocked in cancer cells. The addition of this single amino acid is ...

Scientists are investigating why people in this tiny Italian town keep living to 100 - ScienceAlert

Fri, 01/04/2016 - 03:38
The IndependentScientists are investigating why people in this tiny Italian town keep living to 100ScienceAlertThey will also examine metabolomics, biomes, cognitive dysfunction, and protein biomarkers that are linked to a risk of heart disease, Alzheimer's, kidney disease, and cancer, Amanda Onion reports for Discovery News. "This project will not only help to ...Italian Village Holds Longevity Secret (Rosemary?)Discovery NewsThe Key to Longevity is located in ItalyPravdaAcciaroli, the Italian town that can unlock the secret of longevityContenuti opinionisticiNews-Medical.net -Wisconsin Ag Connectionall 17 news articles »

Living off the fat of the land - EurekAlert (press release)

Thu, 31/03/2016 - 18:06
EurekAlert (press release)Living off the fat of the landEurekAlert (press release)"It has only been possible to think about glucose metabolism at the systems level for the past few years," Patti said, referring to the new discipline of metabolomics. "Before that the technology to follow glucose through all the possible metabolic ...and more »

Do cancer cells synthesize the parts for new cells or scavenge them from the environment? - Medical Xpress

Thu, 31/03/2016 - 18:01
Medical XpressDo cancer cells synthesize the parts for new cells or scavenge them from the environment?Medical Xpress"It has only been possible to think about glucose metabolism at the systems level for the past few years," Patti said, referring to the new discipline of metabolomics. "Before that the technology to follow glucose through all the possible metabolic ...and more »

Terahertz & Infrared Spectroscopy Market by Spectrum and Application Global Forecasts to 2020 - PR Newswire (press release)

Thu, 31/03/2016 - 17:01
Terahertz & Infrared Spectroscopy Market by Spectrum and Application Global Forecasts to 2020PR Newswire (press release)Some of these applications are drug discovery and development, metabolomics, and diagnostics. However, the high cost of instruments is hindering market growth. In 2015, the semiconductor segment is expected to account for the largest share of the ...and more »

Italian Village Holds Longevity Secret (Rosemary?) - Discovery News

Thu, 31/03/2016 - 16:41
Discovery NewsItalian Village Holds Longevity Secret (Rosemary?)Discovery NewsThe team plans to collect blood samples from the village to scour for possible genetic advantages they may carry. They will also distribute surveys that ask about diet, lifestyle and fitness. Finally they will examine metabolomics, biomes, cognitive ...The Key to Longevity is located in ItalyPravdaAcciaroli, the Italian town that can unlock the secret of longevityContenuti opinionisticiResearchers to study people over 100 years old in Acciaroli, Italy to unlock secrets of healthy agingNews-Medical.netWisconsin Ag Connectionall 12 news articles »

The Key to Longevity is located in Italy - Pravda

Thu, 31/03/2016 - 13:01
PravdaThe Key to Longevity is located in ItalyPravda... citizens of Acciaroli to find out what made them all live to one hundred years of age. Tests will focus on metabolomics, biomes, cognitive dysfunction and protein biomarkers indicating risk of heart disease, cancer, kidney disease and Alzheimer's ...Acciaroli, the Italian town that can unlock the secret of longevityContenuti opinionisticiResearchers to study people over 100 years old in Acciaroli, Italy to unlock secrets of healthy agingNews-Medical.netRemote Italian Village Harbors Secrets of Healthy AgingWisconsin Ag Connectionall 9 news articles »

Metabolic fingerprints reveal precise amounts of pork in beef mince - Phys.Org

Thu, 31/03/2016 - 11:48
Metabolic fingerprints reveal precise amounts of pork in beef mincePhys.OrgMetabolomics—the study of the molecules involved in metabolism in a living organism by evaluating tissues for changes—has previously been used successfully as an accurate method of detection in a number of other applications including microbiology, ...

Living Off the Fat of the Land - Newswise (press release)

Thu, 31/03/2016 - 11:35
Newswise (press release)Living Off the Fat of the LandNewswise (press release)“It has only been possible to think about glucose metabolism at the systems level for the past few years,” Patti said, referring to the new discipline of metabolomics. “Before that the technology to follow glucose through all the possible metabolic ...

Scientists design method to tell if your mince is telling porkies - The University of Manchester (press release)

Thu, 31/03/2016 - 10:49
The University of Manchester (press release)Scientists design method to tell if your mince is telling porkiesThe University of Manchester (press release)Metabolomics - the study of the molecules involved in metabolism in a living organism by evaluating tissues for changes - has previously been used successfully as an accurate method of detection in a number of other applications including microbiology, ...Google News

Researchers to study people over 100 years old in Acciaroli, Italy to unlock secrets of healthy aging - News-Medical.net

Wed, 30/03/2016 - 20:37
Researchers to study people over 100 years old in Acciaroli, Italy to unlock secrets of healthy agingNews-Medical.netThe study will also involve tests to look at metabolomics, biomes, cognitive dysfunction and protein biomarkers for risk of heart disease, Alzheimer's, kidney disease and cancer. "This project will not only help to unlock some of the secrets of healthy ...and more »

Galmed Pharma (GLMD) Announces Statistically Significant Aramchol Preclinical Data in Fatty Liver Disease - StreetInsider.com

Wed, 30/03/2016 - 14:23
Galmed Pharma (GLMD) Announces Statistically Significant Aramchol Preclinical Data in Fatty Liver DiseaseStreetInsider.comWe are currently investigating transcriptomics and metabolomics data from this study, which may give new insights into the mechanisms that lead to this anti-fibrotic effect of AramcholTM." Professor Scott Friedman, Chief, Division of Liver Diseases ...and more »

Aramchol™ Demonstrates Significant Anti-Fibrotic Effect in a Pre-clinical Model of Fatty Liver Disease - PR Newswire (press release)

Wed, 30/03/2016 - 14:02
Aramchol™ Demonstrates Significant Anti-Fibrotic Effect in a Pre-clinical Model of Fatty Liver DiseasePR Newswire (press release)We are currently investigating transcriptomics and metabolomics data from this study, which may give new insights into the mechanisms that lead to this anti-fibrotic effect of AramcholTM." Professor Scott Friedman, Chief, Division of Liver Diseases ...and more »

Penn med studies effects of space on twin - The Daily Pennsylvanian

Wed, 30/03/2016 - 08:24
The Daily PennsylvanianPenn med studies effects of space on twinThe Daily Pennsylvanian“Because the twins' study involved taking their bodily fluids to analyze them for genomics, metabolomics and microbiomics, the Kellys will have to agree to what aspects of their biology are shared before the findings are released,” Dinges added. The ...and more »

Mass spectrometry Market by Platform, Single mass spectrometry & by Application - Analysis & Global Forecast to 2020 - PR Newswire (press release)

Tue, 29/03/2016 - 23:53
Mass spectrometry Market by Platform, Single mass spectrometry & by Application - Analysis & Global Forecast to 2020PR Newswire (press release)Some of the applications using mass spectrometry are drug discovery and development, metabolomics, and diagnostics. However, the high cost of instruments and the lack of skilled professionals to operate these highly sophisticated systems are factors ...

Remote Italian village could harbor secrets of healthy aging - Medical Xpress

Tue, 29/03/2016 - 22:47
Remote Italian village could harbor secrets of healthy agingMedical XpressThe study will also involve tests to look at metabolomics, biomes, cognitive dysfunction and protein biomarkers for risk of heart disease, Alzheimer's, kidney disease and cancer. "This project will not only help to unlock some of the secrets of healthy ...

Metabolon and SYNLAB Group Form Commercialization Collaboration for Quantose™ IR Diagnostic - EconoTimes

Tue, 29/03/2016 - 16:03
Metabolon and SYNLAB Group Form Commercialization Collaboration for Quantose™ IR DiagnosticEconoTimesRESEARCH TRIANGLE PARK, N.C., March 29, 2016 -- Metabolon, Inc., the global leader in metabolomics, announced today that it has entered into a commercialization collaboration for its Quantose™ IR diagnostic with SYNLAB Group, the leader in the ...and more »

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