Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

Metabolomics News

Improving risk profiling is key to preventing many GI cancers Spink Health - EurekAlert (press release)

Tue, 27/10/2015 - 13:02
EurekAlert (press release)Improving risk profiling is key to preventing many GI cancers Spink HealthEurekAlert (press release)Metabolomics, which analyses body fluids and tissue samples for particular chemicals, is a relative new technique that also looks promising for the detection of stomach cancer. "We are poised on the brink of having new techniques that should help us ...and more »

Heating Dispute - GenomeWeb

Mon, 26/10/2015 - 17:54
Heating DisputeGenomeWebThis, Stephen Barnes, from the Targeted Metabolomics and Proteomics Laboratory at the University of Alabama, Birmingham, tells Chemical & Engineering News, could be why whole metabolome analyses often identify less than 20 percent of cellular ...

Sperm provide next generation with more than just DNA, Penn study finds - Newsworks.org

Mon, 26/10/2015 - 10:02
Sperm provide next generation with more than just DNA, Penn study findsNewsworks.orgShe got hooked on radio as a AAAS Mass Media Fellow with KUNC-FM in Northern Colorado, writing and producing radio stories about plasma sanitizers, chaos theory and rock climbing, and how to use metabolomics to improve the taste of beer. Jessica is ...

Researchers to investigate earliest signs of type 1 diabetic kidney disease - International Business Times AU

Mon, 26/10/2015 - 09:59
International Business Times AUResearchers to investigate earliest signs of type 1 diabetic kidney diseaseInternational Business Times AU“We want to identify the best markers of kidney disease progression and validate them across different patient cohorts,” said Kumar Sharma, principal investigator and director of the Center for Renal Translational Medicine and the Institute of ...Spotting the Earliest Signs of Type 1 Diabetic Kidney DiseaseUCSD Medical CenterResearchers to Study Biomarkers for Early Detection of Diabetic Kidney DiseaseMD Magazineall 6 news articles »Google News

$5.8 Million NIH Contract to SLU to Fund 'Omics' Research - Saint Louis University

Mon, 26/10/2015 - 07:00
Saint Louis University$5.8 Million NIH Contract to SLU to Fund 'Omics' ResearchSaint Louis UniversityMetabolomics: James Edwards, Ph.D., assistant professor of chemistry at SLU, will study metabolites, which are small molecules produced during life-sustaining chemical processes such as digestion. Metabolomics is a highly complicated and dynamic field, ...

Seeking Better Biofuels - The Biological SCENE

Mon, 26/10/2015 - 06:23
The Biological SCENESeeking Better BiofuelsThe Biological SCENE“We do a lot of proteomics and metabolomics because they are the bread and butter of pathway engineering,” says Paul Adams, JBEI's vice president for technology. With the ability to detect 8,000 proteins made in E. coli per day, he's able to help ...

Human Microbiome Market – Research by Transparency Market Research - Medgadget.com (blog)

Sun, 25/10/2015 - 22:00
Human Microbiome Market – Research by Transparency Market ResearchMedgadget.com (blog)Transcriptomics, metabolomics, proteomics and other such advanced 'omics technologies help measure the biological properties of whole microbial communities, eventually providing insights into interaction between the microbiome and human host that ...

Researchers to Study Biomarkers for Early Detection of Diabetic Kidney Disease - MD Magazine

Sat, 24/10/2015 - 19:20
MD MagazineResearchers to Study Biomarkers for Early Detection of Diabetic Kidney DiseaseMD MagazineAs part of a multi-institutional effort, researchers in the fields of proteomics, lipidomics, and metabolomics will collaborate to discover more effective ways of predicting which patients with type 1 diabetes are at greater risk for developing kidney ...Spotting the Earliest Signs of Type 1 Diabetic Kidney DiseaseUCSD Medical Centerall 5 news articles »

Spotting the Earliest Signs of Type 1 Diabetic Kidney Disease - HealthCanal.com (press release) (blog)

Sat, 24/10/2015 - 04:09
Spotting the Earliest Signs of Type 1 Diabetic Kidney DiseaseHealthCanal.com (press release) (blog)At UC San Diego School of Medicine, researchers will conduct metabolomics analysis to look for metabolites that may serve as chemical signatures of kidney disease. Metabolites are small molecules involved in or produced through metabolic processes in ...and more »

QCScreen: a software tool for data quality control in LC-HRMS based metabolomics - 7thSpace Interactive (press release)

Sat, 24/10/2015 - 02:15
QCScreen: a software tool for data quality control in LC-HRMS based metabolomics7thSpace Interactive (press release)Metabolomics experiments often comprise large numbers of biological samples resulting in huge amounts of data. This data needs to be inspected for plausibility before data evaluation to detect putative sources of error e.g. retention time or mass ...Google News

Researchers Explore Potential Solutions, Underlying Causes of Metabolomics ... - GenomeWeb

Fri, 23/10/2015 - 20:51
Researchers Explore Potential Solutions, Underlying Causes of Metabolomics ...GenomeWebFor instance, in a recent commentary in the Proceedings of the National Academy of Sciences, a group of University of California, San Diego researchers noted that in the average untargeted metabolomics experiment only 1.8 percent of spectra is identified.

How will big data analysis fit into everyday medicine? - Genetic Literacy Project

Fri, 23/10/2015 - 17:15
How will big data analysis fit into everyday medicine?Genetic Literacy ProjectThis will be nothing new for clinical genetics and other niche disciplines, but as medicine begins to mine the rich data streams from genomics, transcriptomics and metabolomics research, we will start running into some rather tricky integration ...Google News

MED-C Secures Cornerstone Funding - MarketWatch

Fri, 23/10/2015 - 13:03
MED-C Secures Cornerstone FundingMarketWatchAfter this pilot project gets off the ground, and as further support is obtained, MED-C plans to open up the NGS registry to other disease states and then through affiliated projects explore testing in areas such as proteomics, immunology, metabolomics ...and more »Google News

Nephrology research—the past, present and future - Nature.com

Fri, 23/10/2015 - 07:47
Nature.comNephrology research—the past, present and futureNature.comGenomics, proteomics and metabolomics will continue to improve our understanding of the molecular and metabolic basis of diseases. Exciting novel genome engineering tools such as the clustered, regularly interspaced palindromic repeat (CRISPR) system ...

Spotting the Earliest Signs of Type 1 Diabetic Kidney Disease - UCSD Medical Center

Thu, 22/10/2015 - 21:35
Spotting the Earliest Signs of Type 1 Diabetic Kidney DiseaseUCSD Medical CenterAt UC San Diego School of Medicine, researchers will conduct metabolomics analysis to look for metabolites that may serve as chemical signatures of kidney disease. Metabolites are small molecules involved in or produced through metabolic processes in ...and more »

Spotting the Earliest Signs of Type 1 Diabetic Kidney Disease - UCSD Medical Center

Thu, 22/10/2015 - 21:35
UCSD Medical CenterSpotting the Earliest Signs of Type 1 Diabetic Kidney DiseaseUCSD Medical CenterAt UC San Diego School of Medicine, researchers will conduct metabolomics analysis to look for metabolites that may serve as chemical signatures of kidney disease. Metabolites are small molecules involved in or produced through metabolic processes in ...and more »

GC-MS Distorts Data? - The Scientist

Thu, 22/10/2015 - 20:01
The ScientistGC-MS Distorts Data?The ScientistThis phenomenon could help explain why such analyses generally identify only 20 percent of cellular metabolites, Stephen Barnes, director of the Targeted Metabolomics & Proteomics Laboratory at the University of Alabama, told C&EN. But the problem ...

Metabolomics reveals metabolic changes in male reproductive cells exposed to thirdhand smoke - Nature.com

Thu, 22/10/2015 - 09:00
Metabolomics reveals metabolic changes in male reproductive cells exposed to thirdhand smoke  Nature.com

Personalized Medicine in Idiopathic Pulmonary Fibrosis - Medscape

Thu, 22/10/2015 - 06:19
Personalized Medicine in Idiopathic Pulmonary FibrosisMedscape... candidate biomarkers are presented based on their proposed mechanistic pathways (e.g. alveolar epithelial cell dysfunction, immune dysregulation, microbiome, extracellular matrix remodeling and fibroproliferation, epigenetic markers and metabolomics).

Heated Dispute Over Analytical Method - The Biological SCENE

Wed, 21/10/2015 - 16:15
The Biological SCENEHeated Dispute Over Analytical MethodThe Biological SCENEThe results question what we are really analyzing when GC-MS experiments are used to identify unknown compounds in a sample, says Siuzdak, a specialist in MS and metabolomics. “The injected sample, or its thermal degradation products?” he asks.

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