Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

A holistic comparison of flavor signature and chemical profile in different harvesting periods of <em>Chrysanthemum morifolium Ramat.</em> based on metabolomics combined with bioinformatics and molecular docking strategy

Wed, 21/12/2022 - 12:00
RSC Adv. 2022 Dec 7;12(54):34971-34989. doi: 10.1039/d2ra05698d. eCollection 2022 Dec 6.NO ABSTRACTPMID:36540235 | PMC:PMC9728093 | DOI:10.1039/d2ra05698d

αA and αB peptides from human cataractous lenses show antichaperone activity and enhance aggregation of lens proteins

Wed, 21/12/2022 - 12:00
Mol Vis. 2022 Aug 6;28:147-164. eCollection 2022.NO ABSTRACTPMID:36540064 | PMC:PMC9744240

Single-cell and spatial multi-omics in the plant sciences: Technical advances, applications, and perspectives

Wed, 21/12/2022 - 12:00
Plant Commun. 2022 Dec 20:100508. doi: 10.1016/j.xplc.2022.100508. Online ahead of print.NO ABSTRACTPMID:36540021 | DOI:10.1016/j.xplc.2022.100508

Definition of a novel breast tumor-specific classifier based on secretome analysis

Tue, 20/12/2022 - 12:00
Breast Cancer Res. 2022 Dec 20;24(1):94. doi: 10.1186/s13058-022-01590-4.NO ABSTRACTPMID:36539890 | DOI:10.1186/s13058-022-01590-4

Elevated circulating level of β-aminoisobutyric acid (BAIBA) in heart failure patients with type 2 diabetes receiving sodium-glucose cotransporter 2 inhibitors

Tue, 20/12/2022 - 12:00
Cardiovasc Diabetol. 2022 Dec 20;21(1):285. doi: 10.1186/s12933-022-01727-x.NO ABSTRACTPMID:36539818 | DOI:10.1186/s12933-022-01727-x

Metabolome and transcriptome profiles in quinoa seedlings in response to potassium supply

Tue, 20/12/2022 - 12:00
BMC Plant Biol. 2022 Dec 21;22(1):604. doi: 10.1186/s12870-022-03928-8.NO ABSTRACTPMID:36539684 | DOI:10.1186/s12870-022-03928-8

Clinical Prognostic Factors and Integrated Multi-Omics Studies Identify Potential Novel Therapeutic Targets for Pediatric Desmoid Tumor

Tue, 20/12/2022 - 12:00
Biol Proced Online. 2022 Dec 20;24(1):25. doi: 10.1186/s12575-022-00180-0.NO ABSTRACTPMID:36539683 | DOI:10.1186/s12575-022-00180-0

Integration of metabolomics and transcriptomics to reveal ferroptosis is involved in Tripterygium wilfordii polyglycoside tablet-induced testicular injury

Tue, 20/12/2022 - 12:00
J Ethnopharmacol. 2022 Dec 17:116055. doi: 10.1016/j.jep.2022.116055. Online ahead of print.NO ABSTRACTPMID:36539070 | DOI:10.1016/j.jep.2022.116055

First Trimester Preterm Preeclampsia Prediction with Metabolite Biomarkers: Differential Prediction According to Maternal Body Mass Index

Tue, 20/12/2022 - 12:00
Am J Obstet Gynecol. 2022 Dec 17:S0002-9378(22)02290-6. doi: 10.1016/j.ajog.2022.12.012. Online ahead of print.NO ABSTRACTPMID:36539025 | DOI:10.1016/j.ajog.2022.12.012

A multi-omic brain gut microbiome signature differs between IBS subjects with different bowel habits

Tue, 20/12/2022 - 12:00
Neuropharmacology. 2022 Dec 17:109381. doi: 10.1016/j.neuropharm.2022.109381. Online ahead of print.NO ABSTRACTPMID:36539012 | DOI:10.1016/j.neuropharm.2022.109381

Changes on proteomic and metabolomic profiling of cryopreserved sperm effected by melatonin

Tue, 20/12/2022 - 12:00
J Proteomics. 2022 Dec 17:104791. doi: 10.1016/j.jprot.2022.104791. Online ahead of print.NO ABSTRACTPMID:36538967 | DOI:10.1016/j.jprot.2022.104791

Simvastatin therapy in higher dosages deteriorates bone quality: Consistent evidence from population-wide patient data and interventional mouse studies

Tue, 20/12/2022 - 12:00
Biomed Pharmacother. 2022 Dec 18;158:114089. doi: 10.1016/j.biopha.2022.114089. Online ahead of print.NO ABSTRACTPMID:36538862 | DOI:10.1016/j.biopha.2022.114089

Normalization Approach by a Reference Material to Improve LC-MS-Based Metabolomic Data Comparability of Multibatch Samples

Tue, 20/12/2022 - 12:00
Anal Chem. 2022 Dec 20. doi: 10.1021/acs.analchem.2c04188. Online ahead of print.NO ABSTRACTPMID:36538611 | DOI:10.1021/acs.analchem.2c04188

Mechanism of Rotenone Toxicity against <em>Plutella xylostella</em>: New Perspective from a Spatial Metabolomics and Lipidomics Study

Tue, 20/12/2022 - 12:00
J Agric Food Chem. 2022 Dec 20. doi: 10.1021/acs.jafc.2c06292. Online ahead of print.NO ABSTRACTPMID:36538414 | DOI:10.1021/acs.jafc.2c06292

Maternal exposure to polystyrene microplastics alters placental metabolism in mice

Tue, 20/12/2022 - 12:00
Metabolomics. 2022 Dec 20;19(1):1. doi: 10.1007/s11306-022-01967-8.NO ABSTRACTPMID:36538272 | DOI:10.1007/s11306-022-01967-8

Disrupting the ArcA Regulatory Network Amplifies the Fitness Cost of Tetracycline Resistance in Escherichia coli

Tue, 20/12/2022 - 12:00
mSystems. 2022 Dec 20:e0090422. doi: 10.1128/msystems.00904-22. Online ahead of print.NO ABSTRACTPMID:36537814 | DOI:10.1128/msystems.00904-22

Exploring the Interspecific Interactions and the Metabolome of the Soil Isolate Hylemonella gracilis

Tue, 20/12/2022 - 12:00
mSystems. 2022 Dec 20:e0057422. doi: 10.1128/msystems.00574-22. Online ahead of print.NO ABSTRACTPMID:36537799 | DOI:10.1128/msystems.00574-22

Cross-talk between red blood cells and plasma influences blood flow and omics phenotypes in severe COVID-19

Tue, 20/12/2022 - 12:00
Elife. 2022 Dec 20;11:e81316. doi: 10.7554/eLife.81316.NO ABSTRACTPMID:36537079 | DOI:10.7554/eLife.81316

Metabonomic Analysis of Metabolites Produced by <em>Escherichia coli</em> in Patients With and Without Sepsis

Tue, 20/12/2022 - 12:00
Infect Drug Resist. 2022 Dec 13;15:7339-7350. doi: 10.2147/IDR.S388034. eCollection 2022.NO ABSTRACTPMID:36536860 | PMC:PMC9759013 | DOI:10.2147/IDR.S388034

Validation of gestational age determination from ultrasound or a metabolic gestational age algorithm using exact date of conception in a cohort of newborns conceived using assisted reproduction technologies

Tue, 20/12/2022 - 12:00
AJOG Glob Rep. 2022 Aug 26;2(4):100091. doi: 10.1016/j.xagr.2022.100091. eCollection 2022 Nov.NO ABSTRACTPMID:36536852 | PMC:PMC9758343 | DOI:10.1016/j.xagr.2022.100091

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