Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies

Mon, 19/12/2022 - 12:00
Clin Cancer Res. 2022 Dec 19:CCR-22-2215. doi: 10.1158/1078-0432.CCR-22-2215. Online ahead of print.NO ABSTRACTPMID:36534518 | DOI:10.1158/1078-0432.CCR-22-2215

Human centenarian-associated SIRT6 mutants modulate hepatocyte metabolism and collagen deposition in multilineage hepatic 3D spheroids

Mon, 19/12/2022 - 12:00
Geroscience. 2022 Dec 19. doi: 10.1007/s11357-022-00713-1. Online ahead of print.NO ABSTRACTPMID:36534275 | DOI:10.1007/s11357-022-00713-1

The effects of extracellular algicidal compounds of Bacillus sp. B1 on Heterosigma akashiwo: a metabolomics approach

Mon, 19/12/2022 - 12:00
Environ Sci Pollut Res Int. 2022 Dec 19. doi: 10.1007/s11356-022-24255-3. Online ahead of print.NO ABSTRACTPMID:36534259 | DOI:10.1007/s11356-022-24255-3

Dysregulation of Amino Acid, Lipid, and Acylpyruvate Metabolism in Idiopathic Intracranial Hypertension: A Non-targeted Case Control and Longitudinal Metabolomic Study

Mon, 19/12/2022 - 12:00
J Proteome Res. 2022 Dec 19. doi: 10.1021/acs.jproteome.2c00449. Online ahead of print.NO ABSTRACTPMID:36534069 | DOI:10.1021/acs.jproteome.2c00449

Microbiome-Metabolomics Analysis of the Impacts of <em>Cryptosporidium muris</em> Infection in BALB/C Mice

Mon, 19/12/2022 - 12:00
Microbiol Spectr. 2022 Dec 19:e0217522. doi: 10.1128/spectrum.02175-22. Online ahead of print.NO ABSTRACTPMID:36533947 | DOI:10.1128/spectrum.02175-22

Untargeted Metabolomics-Assisted Comparative Cytochrome P450-dependent Metabolism of Fenbendazole in Human and Dog Liver Microsomes

Mon, 19/12/2022 - 12:00
Xenobiotica. 2022 Dec 19:1-26. doi: 10.1080/00498254.2022.2160676. Online ahead of print.NO ABSTRACTPMID:36533905 | DOI:10.1080/00498254.2022.2160676

2-hydroxyisobutyric acid (2-HIBA) modulates ageing and fat deposition in <em>Caenorhabditis elegans</em>

Mon, 19/12/2022 - 12:00
Front Mol Biosci. 2022 Nov 23;9:986022. doi: 10.3389/fmolb.2022.986022. eCollection 2022.NO ABSTRACTPMID:36533081 | PMC:PMC9749906 | DOI:10.3389/fmolb.2022.986022

Intestinal flora induces depression by mediating the dysregulation of cerebral cortex gene expression and regulating the metabolism of stroke patients

Mon, 19/12/2022 - 12:00
Front Mol Biosci. 2022 Nov 30;9:865788. doi: 10.3389/fmolb.2022.865788. eCollection 2022.NO ABSTRACTPMID:36533076 | PMC:PMC9748625 | DOI:10.3389/fmolb.2022.865788

Analyzing the Therapeutic Mechanism of Mongolian Medicine <em>Zhonglun</em>-5 in Rheumatoid Arthritis Using a Bagging Algorithm with Serum Metabonomics

Mon, 19/12/2022 - 12:00
Evid Based Complement Alternat Med. 2022 Dec 7;2022:5997562. doi: 10.1155/2022/5997562. eCollection 2022.NO ABSTRACTPMID:36532854 | PMC:PMC9750765 | DOI:10.1155/2022/5997562

Potential mechanisms of Lian-Zhi-Fan solution for TNBS-induced ulcerative colitis in rats <em>via</em> a metabolomics approach

Mon, 19/12/2022 - 12:00
Front Pharmacol. 2022 Dec 2;13:1014117. doi: 10.3389/fphar.2022.1014117. eCollection 2022.NO ABSTRACTPMID:36532763 | PMC:PMC9755326 | DOI:10.3389/fphar.2022.1014117

Combined metabolomics and network pharmacology to elucidate the mechanisms of Dracorhodin Perchlorate in treating diabetic foot ulcer rats

Mon, 19/12/2022 - 12:00
Front Pharmacol. 2022 Nov 18;13:1038656. doi: 10.3389/fphar.2022.1038656. eCollection 2022.NO ABSTRACTPMID:36532755 | PMC:PMC9752146 | DOI:10.3389/fphar.2022.1038656

Integration of transcriptomics and metabolomics reveals the molecular mechanisms underlying the effect of nafamostat mesylate on rhabdomyolysis-induced acute kidney injury

Mon, 19/12/2022 - 12:00
Front Pharmacol. 2022 Nov 29;13:931670. doi: 10.3389/fphar.2022.931670. eCollection 2022.NO ABSTRACTPMID:36532745 | PMC:PMC9748812 | DOI:10.3389/fphar.2022.931670

Comprehensive serum metabolomics and network analysis to reveal the mechanism of gypenosides in treating lung cancer and enhancing the pharmacological effects of cisplatin

Mon, 19/12/2022 - 12:00
Front Pharmacol. 2022 Dec 1;13:1070948. doi: 10.3389/fphar.2022.1070948. eCollection 2022.NO ABSTRACTPMID:36532716 | PMC:PMC9751056 | DOI:10.3389/fphar.2022.1070948

Polyphenols of Perilla frutescens of the family Lamiaceae identified by tandem mass spectrometry

Mon, 19/12/2022 - 12:00
Vavilovskii Zhurnal Genet Selektsii. 2022 Nov;26(7):637-644. doi: 10.18699/VJGB-22-78.NO ABSTRACTPMID:36532628 | PMC:PMC9727548 | DOI:10.18699/VJGB-22-78

Metabolomic prof iles of Ribes nigrum L. and Lonicera caerulea L. from the collection of the N.I. Vavilov Institute in the setting of Northwest Russia

Mon, 19/12/2022 - 12:00
Vavilovskii Zhurnal Genet Selektsii. 2022 Nov;26(7):630-636. doi: 10.18699/VJGB-22-77.NO ABSTRACTPMID:36532621 | PMC:PMC9727547 | DOI:10.18699/VJGB-22-77

Omega 3 supplementation reduces C-reactive protein, prostaglandin E<sub>2</sub> and the granulocyte/lymphocyte ratio in heavy smokers: An open-label randomized crossover trial

Mon, 19/12/2022 - 12:00
Front Nutr. 2022 Dec 1;9:1051418. doi: 10.3389/fnut.2022.1051418. eCollection 2022.NO ABSTRACTPMID:36532545 | PMC:PMC9751896 | DOI:10.3389/fnut.2022.1051418

Glutamine potentiates gentamicin to kill lab-evolved gentamicin-resistant and clinically isolated multidrug-resistant <em>Escherichia coli</em>

Mon, 19/12/2022 - 12:00
Front Microbiol. 2022 Dec 2;13:1071278. doi: 10.3389/fmicb.2022.1071278. eCollection 2022.NO ABSTRACTPMID:36532472 | PMC:PMC9755591 | DOI:10.3389/fmicb.2022.1071278

Rumen-protected glucose supplementation alters fecal microbiota and its metabolic profiles in early lactation dairy cows

Mon, 19/12/2022 - 12:00
Front Microbiol. 2022 Dec 2;13:1034675. doi: 10.3389/fmicb.2022.1034675. eCollection 2022.NO ABSTRACTPMID:36532465 | PMC:PMC9755595 | DOI:10.3389/fmicb.2022.1034675

Systematic analysis of Baobaoqu fermentation starter for <em>Wuliangye</em> Baijiu by the combination of metagenomics and metabolomics

Mon, 19/12/2022 - 12:00
Front Microbiol. 2022 Dec 1;13:1062547. doi: 10.3389/fmicb.2022.1062547. eCollection 2022.NO ABSTRACTPMID:36532455 | PMC:PMC9751829 | DOI:10.3389/fmicb.2022.1062547

Chronic alcohol-induced dysbiosis of the gut microbiota and gut metabolites impairs sperm quality in mice

Mon, 19/12/2022 - 12:00
Front Microbiol. 2022 Dec 1;13:1042923. doi: 10.3389/fmicb.2022.1042923. eCollection 2022.NO ABSTRACTPMID:36532416 | PMC:PMC9751024 | DOI:10.3389/fmicb.2022.1042923

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