Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

GSK3 inhibitor suppresses cell growth and metabolic process in FLT3-ITD leukemia cells

Fri, 09/12/2022 - 12:00
Med Oncol. 2022 Dec 8;40(1):44. doi: 10.1007/s12032-022-01899-2.NO ABSTRACTPMID:36481875 | DOI:10.1007/s12032-022-01899-2

Quality evaluation of ginkgo biloba leaves based on non-targeted metabolomics and representative ingredient quantification

Fri, 09/12/2022 - 12:00
J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Nov 26;1214:123549. doi: 10.1016/j.jchromb.2022.123549. Online ahead of print.NO ABSTRACTPMID:36481725 | DOI:10.1016/j.jchromb.2022.123549

Research Note: Integrated transcriptomic and metabolomic analysis reveals potential candidate genes and regulatory pathways associated with egg weight in ducks

Thu, 08/12/2022 - 12:00
Poult Sci. 2022 Nov 14;102(2):102341. doi: 10.1016/j.psj.2022.102341. Online ahead of print.NO ABSTRACTPMID:36481710 | DOI:10.1016/j.psj.2022.102341

The role of the tryptophan-NAD + pathway in a mouse model of severe malnutrition induced liver dysfunction

Thu, 08/12/2022 - 12:00
Nat Commun. 2022 Dec 8;13(1):7576. doi: 10.1038/s41467-022-35317-y.NO ABSTRACTPMID:36481684 | DOI:10.1038/s41467-022-35317-y

Graphene Quantum Dots Disturbed the Energy Homeostasis by Influencing Lipid Metabolism of Macrophages

Thu, 08/12/2022 - 12:00
Toxicology. 2022 Dec 5:153389. doi: 10.1016/j.tox.2022.153389. Online ahead of print.NO ABSTRACTPMID:36481571 | DOI:10.1016/j.tox.2022.153389

Untargeted metabolomics description of propolis's in vitro antibacterial mechanisms against Clostridium perfringens

Thu, 08/12/2022 - 12:00
Food Chem. 2022 Nov 26;406:135061. doi: 10.1016/j.foodchem.2022.135061. Online ahead of print.NO ABSTRACTPMID:36481515 | DOI:10.1016/j.foodchem.2022.135061

Distinct effects of intracellular vs. extracellular acidic pH on the cardiac metabolome during ischemia and reperfusion

Thu, 08/12/2022 - 12:00
J Mol Cell Cardiol. 2022 Dec 5;174:101-114. doi: 10.1016/j.yjmcc.2022.11.008. Online ahead of print.NO ABSTRACTPMID:36481511 | DOI:10.1016/j.yjmcc.2022.11.008

Inhibitory effects of Ganoderma lucidum spore oil on rheumatoid arthritis in a collagen-induced arthritis mouse model

Thu, 08/12/2022 - 12:00
Biomed Pharmacother. 2022 Dec 5;157:114067. doi: 10.1016/j.biopha.2022.114067. Online ahead of print.NO ABSTRACTPMID:36481405 | DOI:10.1016/j.biopha.2022.114067

Integrating transcriptome and metabolome to identify key genes regulating important muscular flavour precursors in sheep

Thu, 08/12/2022 - 12:00
Animal. 2022 Nov 12;16(12):100679. doi: 10.1016/j.animal.2022.100679. Online ahead of print.NO ABSTRACTPMID:36481351 | DOI:10.1016/j.animal.2022.100679

Mechanism of Jinzhen Oral Liquid against influenza-induced lung injury based on metabonomics and gut microbiome

Thu, 08/12/2022 - 12:00
J Ethnopharmacol. 2022 Dec 5:115977. doi: 10.1016/j.jep.2022.115977. Online ahead of print.NO ABSTRACTPMID:36481245 | DOI:10.1016/j.jep.2022.115977

Integrated metabolomics and molecular docking reveal berberrubine inhibits thrombosis by regulating the vitamin K catalytic cycle in mice

Thu, 08/12/2022 - 12:00
Eur J Pharmacol. 2022 Dec 5:175436. doi: 10.1016/j.ejphar.2022.175436. Online ahead of print.NO ABSTRACTPMID:36481237 | DOI:10.1016/j.ejphar.2022.175436

Distinct Quality Changes of Asparagus during Growth by Widely Targeted Metabolomics Analysis

Thu, 08/12/2022 - 12:00
J Agric Food Chem. 2022 Dec 8. doi: 10.1021/acs.jafc.2c05743. Online ahead of print.NO ABSTRACTPMID:36480912 | DOI:10.1021/acs.jafc.2c05743

AMPK regulates homeostasis of invasion and viability in trophoblasts by redirecting glucose metabolism: Implications for pre-eclampsia

Thu, 08/12/2022 - 12:00
Cell Prolif. 2022 Dec 8:e13358. doi: 10.1111/cpr.13358. Online ahead of print.NO ABSTRACTPMID:36480593 | DOI:10.1111/cpr.13358

Drug resistance mechanisms create targetable proteostatic vulnerabilities in Her2+ breast cancers

Thu, 08/12/2022 - 12:00
PLoS One. 2022 Dec 8;17(12):e0256788. doi: 10.1371/journal.pone.0256788. eCollection 2022.NO ABSTRACTPMID:36480552 | DOI:10.1371/journal.pone.0256788

Metabolomics analysis of the serum metabolic signature of the nonalcoholic fatty liver disease combined with prediabetes model rats after the intervention of Lycium barbarum polysaccharides combined with aerobic activity

Thu, 08/12/2022 - 12:00
Biomed Chromatogr. 2022 Dec 8:e5562. doi: 10.1002/bmc.5562. Online ahead of print.NO ABSTRACTPMID:36480472 | DOI:10.1002/bmc.5562

Breast Milk-Derived Limosilactobacillus reuteri Prevents Atopic Dermatitis in Mice via Activating Retinol Absorption and Metabolism in Peyer's Patches

Thu, 08/12/2022 - 12:00
Mol Nutr Food Res. 2022 Dec 8:e2200444. doi: 10.1002/mnfr.202200444. Online ahead of print.NO ABSTRACTPMID:36480309 | DOI:10.1002/mnfr.202200444

IgG Fab Glycans Hinder FcRn-Mediated Placental Transport

Thu, 08/12/2022 - 12:00
J Immunol. 2022 Dec 7:ji2200438. doi: 10.4049/jimmunol.2200438. Online ahead of print.NO ABSTRACTPMID:36480251 | DOI:10.4049/jimmunol.2200438

Elevated methionine flux drives pyroptosis evasion in persister cancer cells

Thu, 08/12/2022 - 12:00
Cancer Res. 2022 Dec 8:CAN-22-1002. doi: 10.1158/0008-5472.CAN-22-1002. Online ahead of print.NO ABSTRACTPMID:36480167 | DOI:10.1158/0008-5472.CAN-22-1002

Isolated murine skeletal muscles utilize pyruvate over glucose for oxidation

Thu, 08/12/2022 - 12:00
Metabolomics. 2022 Dec 8;18(12):105. doi: 10.1007/s11306-022-01948-x.NO ABSTRACTPMID:36480060 | DOI:10.1007/s11306-022-01948-x

Convergent Approaches to Delineate the Metabolic Regulation of Tumor Invasion by Hyaluronic Acid Biosynthesis

Thu, 08/12/2022 - 12:00
Adv Healthc Mater. 2022 Dec 8:e2202224. doi: 10.1002/adhm.202202224. Online ahead of print.NO ABSTRACTPMID:36479976 | DOI:10.1002/adhm.202202224

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