Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

Ribitol alters multiple metabolic pathways of central carbon metabolism with enhanced glycolysis: A metabolomics and transcriptomics profiling of breast cancer

Thu, 08/12/2022 - 12:00
PLoS One. 2022 Dec 7;17(12):e0278711. doi: 10.1371/journal.pone.0278711. eCollection 2022.NO ABSTRACTPMID:36477459 | DOI:10.1371/journal.pone.0278711

Lipid desaturation regulates the balance between self-renewal and differentiation in mouse blastocyst-derived stem cells

Thu, 08/12/2022 - 12:00
Cell Death Dis. 2022 Dec 7;13(12):1027. doi: 10.1038/s41419-022-05263-0.NO ABSTRACTPMID:36477438 | DOI:10.1038/s41419-022-05263-0

Liver-derived metabolites as signaling molecules in fatty liver disease

Thu, 08/12/2022 - 12:00
Cell Mol Life Sci. 2022 Dec 7;80(1):4. doi: 10.1007/s00018-022-04658-8.NO ABSTRACTPMID:36477411 | DOI:10.1007/s00018-022-04658-8

Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning

Thu, 08/12/2022 - 12:00
Cell Rep. 2022 Dec 6;41(10):111766. doi: 10.1016/j.celrep.2022.111766.NO ABSTRACTPMID:36476872 | DOI:10.1016/j.celrep.2022.111766

Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence

Thu, 08/12/2022 - 12:00
Cell Rep. 2022 Dec 6;41(10):111756. doi: 10.1016/j.celrep.2022.111756.NO ABSTRACTPMID:36476868 | DOI:10.1016/j.celrep.2022.111756

Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation

Thu, 08/12/2022 - 12:00
Cell Rep. 2022 Dec 6;41(10):111761. doi: 10.1016/j.celrep.2022.111761.NO ABSTRACTPMID:36476851 | DOI:10.1016/j.celrep.2022.111761

Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage

Thu, 08/12/2022 - 12:00
Sci Transl Med. 2022 Dec 7;14(674):eabj4375. doi: 10.1126/scitranslmed.abj4375. Epub 2022 Dec 7.NO ABSTRACTPMID:36475903 | DOI:10.1126/scitranslmed.abj4375

Taxonomic and Metagenomic Analyses Define the Development of the Microbiota in the Chick

Thu, 08/12/2022 - 12:00
mBio. 2022 Dec 8:e0244422. doi: 10.1128/mbio.02444-22. Online ahead of print.NO ABSTRACTPMID:36475774 | DOI:10.1128/mbio.02444-22

An Untargeted Metabolomics Workflow that Scales to Thousands of Samples for Population-Based Studies

Thu, 08/12/2022 - 12:00
Anal Chem. 2022 Dec 7. doi: 10.1021/acs.analchem.2c01270. Online ahead of print.NO ABSTRACTPMID:36475608 | DOI:10.1021/acs.analchem.2c01270

Identification of a differential metabolite-based signature in patients with late-stage knee osteoarthritis

Wed, 07/12/2022 - 12:00
Osteoarthr Cartil Open. 2022 Apr 2;4(3):100258. doi: 10.1016/j.ocarto.2022.100258. eCollection 2022 Sep.NO ABSTRACTPMID:36474953 | PMC:PMC9718221 | DOI:10.1016/j.ocarto.2022.100258

Synovial tissue metabolomic profiling reveal biomarkers of synovial inflammation in patients with osteoarthritis

Wed, 07/12/2022 - 12:00
Osteoarthr Cartil Open. 2022 Jul 9;4(3):100295. doi: 10.1016/j.ocarto.2022.100295. eCollection 2022 Sep.NO ABSTRACTPMID:36474936 | PMC:PMC9718344 | DOI:10.1016/j.ocarto.2022.100295

Postprandial Metabolome Following a Low Glycaemic Index Meal-Challenge Test: A Narrative Review

Wed, 07/12/2022 - 12:00
Malays J Med Sci. 2022 Oct;29(5):5-16. doi: 10.21315/mjms2022.29.5.2. Epub 2022 Oct 28.NO ABSTRACTPMID:36474545 | PMC:PMC9680996 | DOI:10.21315/mjms2022.29.5.2

<em>In vivo</em> mechanotransduction: Effect of acute exercise on the metabolomic profiles of mouse synovial fluid

Wed, 07/12/2022 - 12:00
Osteoarthr Cartil Open. 2021 Dec 8;4(1):100228. doi: 10.1016/j.ocarto.2021.100228. eCollection 2022 Mar.NO ABSTRACTPMID:36474473 | PMC:PMC9718234 | DOI:10.1016/j.ocarto.2021.100228

Metabolome-Wide Reprogramming Modulated by Wnt/β-Catenin Signaling Pathway

Wed, 07/12/2022 - 12:00
J Microbiol Biotechnol. 2022 Nov 18;33(1):1-9. doi: 10.4014/jmb.2211.11013. Online ahead of print.NO ABSTRACTPMID:36474320 | DOI:10.4014/jmb.2211.11013

The sex-specific metabolic signature of C57BL/6NRj mice during aging

Tue, 06/12/2022 - 12:00
Sci Rep. 2022 Dec 6;12(1):21050. doi: 10.1038/s41598-022-25396-8.NO ABSTRACTPMID:36473898 | DOI:10.1038/s41598-022-25396-8

<sup>1</sup>H NMR metabolomics analysis of oil palm stem tissue infected by Ganoderma boninense based on field severity Indices

Tue, 06/12/2022 - 12:00
Sci Rep. 2022 Dec 6;12(1):21087. doi: 10.1038/s41598-022-25450-5.NO ABSTRACTPMID:36473892 | DOI:10.1038/s41598-022-25450-5

Metabolic Profiling of <em>Oryza sativa</em> L. Triggered by Chilling Stress Using Ultraperformance Liquid Chromatography Coupled with Quadrupole/Time-of-Flight Mass Spectrometry (UPLC-QTOF-MS) with Transcriptome Analysis

Tue, 06/12/2022 - 12:00
J Agric Food Chem. 2022 Dec 6. doi: 10.1021/acs.jafc.2c05949. Online ahead of print.NO ABSTRACTPMID:36473722 | DOI:10.1021/acs.jafc.2c05949

Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats

Tue, 06/12/2022 - 12:00
J Ethnopharmacol. 2022 Dec 3:116007. doi: 10.1016/j.jep.2022.116007. Online ahead of print.NO ABSTRACTPMID:36473618 | DOI:10.1016/j.jep.2022.116007

Integrated analysis of transcriptomics and metabolomics in human hepatocellular carcinoma HepG2215 cells after YAP1 knockdown

Tue, 06/12/2022 - 12:00
Acta Histochem. 2022 Dec 3;125(1):151987. doi: 10.1016/j.acthis.2022.151987. Online ahead of print.NO ABSTRACTPMID:36473310 | DOI:10.1016/j.acthis.2022.151987

A simple LC-MS/MS method for the simultaneous quantification of drug metabolic enzymes

Tue, 06/12/2022 - 12:00
J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Nov 29;1214:123536. doi: 10.1016/j.jchromb.2022.123536. Online ahead of print.NO ABSTRACTPMID:36473299 | DOI:10.1016/j.jchromb.2022.123536

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