Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota

Mon, 05/12/2022 - 12:00
CNS Neurosci Ther. 2022 Dec 5. doi: 10.1111/cns.14043. Online ahead of print.NO ABSTRACTPMID:36468415 | DOI:10.1111/cns.14043

Identification of proline, 1-pyrroline-5-carboxylate and glutamic acid as biomarkers of depression reflecting brain metabolism using carboxylomics, a new metabolomics method

Mon, 05/12/2022 - 12:00
Psychiatry Clin Neurosci. 2022 Dec 5. doi: 10.1111/pcn.13517. Online ahead of print.NO ABSTRACTPMID:36468242 | DOI:10.1111/pcn.13517

Ultrahigh-Resolution Homo- and Heterodecoupled <sup>1</sup>H and TOCSY NMR Experiments

Mon, 05/12/2022 - 12:00
ACS Omega. 2022 Nov 15;7(47):43283-43289. doi: 10.1021/acsomega.2c06102. eCollection 2022 Nov 29.NO ABSTRACTPMID:36467931 | PMC:PMC9713892 | DOI:10.1021/acsomega.2c06102

Diving into the Molecular Diversity of <em>Aplysina cavernicola's</em> Exometabolites: Contribution of Bromo-Spiroisoxazoline Alkaloids

Mon, 05/12/2022 - 12:00
ACS Omega. 2022 Nov 16;7(47):43068-43083. doi: 10.1021/acsomega.2c05415. eCollection 2022 Nov 29.NO ABSTRACTPMID:36467926 | PMC:PMC9713894 | DOI:10.1021/acsomega.2c05415

Proteomics and metagenomics reveal the relationship between microbial metabolism and protein hydrolysis in dried fermented grass carp using a lactic acid bacteria starter culture

Mon, 05/12/2022 - 12:00
Curr Res Food Sci. 2022 Nov 26;5:2316-2328. doi: 10.1016/j.crfs.2022.11.016. eCollection 2022.NO ABSTRACTPMID:36467746 | PMC:PMC9712823 | DOI:10.1016/j.crfs.2022.11.016

Differences of energy adaptation strategies in <em>Tupaia belangeri</em> between Pianma and Tengchong region by metabolomics of liver: Role of warmer temperature

Mon, 05/12/2022 - 12:00
Front Physiol. 2022 Nov 17;13:1068636. doi: 10.3389/fphys.2022.1068636. eCollection 2022.NO ABSTRACTPMID:36467696 | PMC:PMC9713704 | DOI:10.3389/fphys.2022.1068636

The metabolomic differential plasma profile between dialysates. Pursuing to understand the mechanisms of citrate dialysate clinical benefits

Mon, 05/12/2022 - 12:00
Front Physiol. 2022 Nov 16;13:1013335. doi: 10.3389/fphys.2022.1013335. eCollection 2022.NO ABSTRACTPMID:36467686 | PMC:PMC9709283 | DOI:10.3389/fphys.2022.1013335

Pharmacometabolomic study of drug response to antihypertensive medications for hypertension marker identification in Han Chinese individuals in Taiwan

Mon, 05/12/2022 - 12:00
Comput Struct Biotechnol J. 2022 Nov 17;20:6458-6466. doi: 10.1016/j.csbj.2022.11.030. eCollection 2022.NO ABSTRACTPMID:36467587 | PMC:PMC9708446 | DOI:10.1016/j.csbj.2022.11.030

A case for genomic medicine in South African paediatric patients with neuromuscular disease

Mon, 05/12/2022 - 12:00
Front Pediatr. 2022 Nov 17;10:1033299. doi: 10.3389/fped.2022.1033299. eCollection 2022.NO ABSTRACTPMID:36467485 | PMC:PMC9713312 | DOI:10.3389/fped.2022.1033299

Metabolomics- and systems toxicology-based hepatotoxicity mechanism of <em>Sophorae Tonkinensis Radix et Rhizoma</em> in rats

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 18;13:1015008. doi: 10.3389/fphar.2022.1015008. eCollection 2022.NO ABSTRACTPMID:36467100 | PMC:PMC9717682 | DOI:10.3389/fphar.2022.1015008

Disturbing effect of cepharanthine on valve interstitial cells calcification <em>via</em> regulating glycolytic metabolism pathways

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 17;13:1070922. doi: 10.3389/fphar.2022.1070922. eCollection 2022.NO ABSTRACTPMID:36467082 | PMC:PMC9714323 | DOI:10.3389/fphar.2022.1070922

Integrated analysis of comprehensive metabolomics and network pharmacology to reveal the mechanisms of <em>abelmoschus manihot</em> (L.) medik. in the treatment of cisplatin-induced chronic kidney disease

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 18;13:1064498. doi: 10.3389/fphar.2022.1064498. eCollection 2022.NO ABSTRACTPMID:36467079 | PMC:PMC9715753 | DOI:10.3389/fphar.2022.1064498

Zhilong Huoxue Tongyu Capsules' Effects on ischemic stroke: An assessment using fecal 16S rRNA gene sequencing and untargeted serum metabolomics

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 18;13:1052110. doi: 10.3389/fphar.2022.1052110. eCollection 2022.NO ABSTRACTPMID:36467061 | PMC:PMC9715974 | DOI:10.3389/fphar.2022.1052110

Editorial: Development, assessment, improvement, and standardization of methods in herbal drug research

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 16;13:1071194. doi: 10.3389/fphar.2022.1071194. eCollection 2022.NO ABSTRACTPMID:36467043 | PMC:PMC9710377 | DOI:10.3389/fphar.2022.1071194

Yangyinqingfei decoction attenuates PM<sub>2.5</sub>-induced lung injury by enhancing arachidonic acid metabolism

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 16;13:1056078. doi: 10.3389/fphar.2022.1056078. eCollection 2022.NO ABSTRACTPMID:36467030 | PMC:PMC9708729 | DOI:10.3389/fphar.2022.1056078

<em>Clostridium butyricum</em> potentially improves inflammation and immunity through alteration of the microbiota and metabolism of gastric cancer patients after gastrectomy

Mon, 05/12/2022 - 12:00
Front Immunol. 2022 Nov 17;13:1076245. doi: 10.3389/fimmu.2022.1076245. eCollection 2022.NO ABSTRACTPMID:36466862 | PMC:PMC9714544 | DOI:10.3389/fimmu.2022.1076245

Cow's microbiome from antepartum to postpartum: A long-term study covering two physiological challenges

Mon, 05/12/2022 - 12:00
Front Microbiol. 2022 Nov 16;13:1000750. doi: 10.3389/fmicb.2022.1000750. eCollection 2022.NO ABSTRACTPMID:36466656 | PMC:PMC9709127 | DOI:10.3389/fmicb.2022.1000750

Long-term fasting: Multi-system adaptations in humans (GENESIS) study-A single-arm interventional trial

Mon, 05/12/2022 - 12:00
Front Nutr. 2022 Nov 17;9:951000. doi: 10.3389/fnut.2022.951000. eCollection 2022.NO ABSTRACTPMID:36466423 | PMC:PMC9713250 | DOI:10.3389/fnut.2022.951000

Neuroprotection of cannabidiol in epileptic rats: Gut microbiome and metabolome sequencing

Mon, 05/12/2022 - 12:00
Front Nutr. 2022 Nov 16;9:1028459. doi: 10.3389/fnut.2022.1028459. eCollection 2022.NO ABSTRACTPMID:36466385 | PMC:PMC9709218 | DOI:10.3389/fnut.2022.1028459

Integrated transcriptomic and metabolic analyses provide insights into the maintenance of embryogenic potential and the biosynthesis of phenolic acids and flavonoids involving transcription factors in <em>Larix kaempferi</em> (Lamb.) Carr

Mon, 05/12/2022 - 12:00
Front Plant Sci. 2022 Nov 17;13:1056930. doi: 10.3389/fpls.2022.1056930. eCollection 2022.NO ABSTRACTPMID:36466286 | PMC:PMC9714495 | DOI:10.3389/fpls.2022.1056930

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