Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

Metabolomics- and systems toxicology-based hepatotoxicity mechanism of <em>Sophorae Tonkinensis Radix et Rhizoma</em> in rats

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 18;13:1015008. doi: 10.3389/fphar.2022.1015008. eCollection 2022.NO ABSTRACTPMID:36467100 | PMC:PMC9717682 | DOI:10.3389/fphar.2022.1015008

Disturbing effect of cepharanthine on valve interstitial cells calcification <em>via</em> regulating glycolytic metabolism pathways

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 17;13:1070922. doi: 10.3389/fphar.2022.1070922. eCollection 2022.NO ABSTRACTPMID:36467082 | PMC:PMC9714323 | DOI:10.3389/fphar.2022.1070922

Integrated analysis of comprehensive metabolomics and network pharmacology to reveal the mechanisms of <em>abelmoschus manihot</em> (L.) medik. in the treatment of cisplatin-induced chronic kidney disease

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 18;13:1064498. doi: 10.3389/fphar.2022.1064498. eCollection 2022.NO ABSTRACTPMID:36467079 | PMC:PMC9715753 | DOI:10.3389/fphar.2022.1064498

Zhilong Huoxue Tongyu Capsules' Effects on ischemic stroke: An assessment using fecal 16S rRNA gene sequencing and untargeted serum metabolomics

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 18;13:1052110. doi: 10.3389/fphar.2022.1052110. eCollection 2022.NO ABSTRACTPMID:36467061 | PMC:PMC9715974 | DOI:10.3389/fphar.2022.1052110

Editorial: Development, assessment, improvement, and standardization of methods in herbal drug research

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 16;13:1071194. doi: 10.3389/fphar.2022.1071194. eCollection 2022.NO ABSTRACTPMID:36467043 | PMC:PMC9710377 | DOI:10.3389/fphar.2022.1071194

Yangyinqingfei decoction attenuates PM<sub>2.5</sub>-induced lung injury by enhancing arachidonic acid metabolism

Mon, 05/12/2022 - 12:00
Front Pharmacol. 2022 Nov 16;13:1056078. doi: 10.3389/fphar.2022.1056078. eCollection 2022.NO ABSTRACTPMID:36467030 | PMC:PMC9708729 | DOI:10.3389/fphar.2022.1056078

<em>Clostridium butyricum</em> potentially improves inflammation and immunity through alteration of the microbiota and metabolism of gastric cancer patients after gastrectomy

Mon, 05/12/2022 - 12:00
Front Immunol. 2022 Nov 17;13:1076245. doi: 10.3389/fimmu.2022.1076245. eCollection 2022.NO ABSTRACTPMID:36466862 | PMC:PMC9714544 | DOI:10.3389/fimmu.2022.1076245

Cow's microbiome from antepartum to postpartum: A long-term study covering two physiological challenges

Mon, 05/12/2022 - 12:00
Front Microbiol. 2022 Nov 16;13:1000750. doi: 10.3389/fmicb.2022.1000750. eCollection 2022.NO ABSTRACTPMID:36466656 | PMC:PMC9709127 | DOI:10.3389/fmicb.2022.1000750

Long-term fasting: Multi-system adaptations in humans (GENESIS) study-A single-arm interventional trial

Mon, 05/12/2022 - 12:00
Front Nutr. 2022 Nov 17;9:951000. doi: 10.3389/fnut.2022.951000. eCollection 2022.NO ABSTRACTPMID:36466423 | PMC:PMC9713250 | DOI:10.3389/fnut.2022.951000

Neuroprotection of cannabidiol in epileptic rats: Gut microbiome and metabolome sequencing

Mon, 05/12/2022 - 12:00
Front Nutr. 2022 Nov 16;9:1028459. doi: 10.3389/fnut.2022.1028459. eCollection 2022.NO ABSTRACTPMID:36466385 | PMC:PMC9709218 | DOI:10.3389/fnut.2022.1028459

Integrated transcriptomic and metabolic analyses provide insights into the maintenance of embryogenic potential and the biosynthesis of phenolic acids and flavonoids involving transcription factors in <em>Larix kaempferi</em> (Lamb.) Carr

Mon, 05/12/2022 - 12:00
Front Plant Sci. 2022 Nov 17;13:1056930. doi: 10.3389/fpls.2022.1056930. eCollection 2022.NO ABSTRACTPMID:36466286 | PMC:PMC9714495 | DOI:10.3389/fpls.2022.1056930

Editorial: Multi-omics and computational biology in horticultural plants: From genotype to phenotype

Mon, 05/12/2022 - 12:00
Front Plant Sci. 2022 Nov 16;13:1073266. doi: 10.3389/fpls.2022.1073266. eCollection 2022.NO ABSTRACTPMID:36466270 | PMC:PMC9709487 | DOI:10.3389/fpls.2022.1073266

Screening for broad-spectrum antimicrobial endophytes from <em>Rosa roxburghii</em> and multi-omic analyses of biosynthetic capacity

Mon, 05/12/2022 - 12:00
Front Plant Sci. 2022 Nov 16;13:1060478. doi: 10.3389/fpls.2022.1060478. eCollection 2022.NO ABSTRACTPMID:36466255 | PMC:PMC9709285 | DOI:10.3389/fpls.2022.1060478

A mass spectrometry imaging approach on spatiotemporal distribution of multiple alkaloids in <em>Gelsemium elegans</em>

Mon, 05/12/2022 - 12:00
Front Plant Sci. 2022 Nov 18;13:1051756. doi: 10.3389/fpls.2022.1051756. eCollection 2022.NO ABSTRACTPMID:36466241 | PMC:PMC9718364 | DOI:10.3389/fpls.2022.1051756

Integrating transcriptomic and metabolomic analysis in roots of wild soybean seedlings in response to low-phosphorus stress

Mon, 05/12/2022 - 12:00
Front Plant Sci. 2022 Nov 17;13:1006806. doi: 10.3389/fpls.2022.1006806. eCollection 2022.NO ABSTRACTPMID:36466240 | PMC:PMC9713585 | DOI:10.3389/fpls.2022.1006806

Revealing the mechanisms of the bioactive ingredients accumulation in <em>Polygonatum cyrtonema</em> by multiomics analyses

Mon, 05/12/2022 - 12:00
Front Plant Sci. 2022 Nov 16;13:1055721. doi: 10.3389/fpls.2022.1055721. eCollection 2022.NO ABSTRACTPMID:36466239 | PMC:PMC9709641 | DOI:10.3389/fpls.2022.1055721

Metabolic dysfunctions promoted by AIN-93G standard diet compared with three obesity-inducing diets in C57BL/6J mice

Mon, 05/12/2022 - 12:00
Curr Res Physiol. 2022 Nov 23;5:436-444. doi: 10.1016/j.crphys.2022.11.001. eCollection 2022.NO ABSTRACTPMID:36466151 | PMC:PMC9713253 | DOI:10.1016/j.crphys.2022.11.001

Microbiome-Metabolome Analysis of the Immune Microenvironment of the Cecal Contents, Soft Feces, and Hard Feces of Hyplus Rabbits

Mon, 05/12/2022 - 12:00
Oxid Med Cell Longev. 2022 Oct 30;2022:5725442. doi: 10.1155/2022/5725442. eCollection 2022.NO ABSTRACTPMID:36466090 | PMC:PMC9713467 | DOI:10.1155/2022/5725442

Proteomic analysis of urinary extracellular vesicles of kidney transplant recipients with BKV viruria and viremia: A pilot study

Mon, 05/12/2022 - 12:00
Front Med (Lausanne). 2022 Nov 17;9:1028085. doi: 10.3389/fmed.2022.1028085. eCollection 2022.NO ABSTRACTPMID:36465937 | PMC:PMC9712214 | DOI:10.3389/fmed.2022.1028085

Serum myo-inositol and valine improve metabolomic-based estimated glomerular filtration rate among kidney transplant recipients

Mon, 05/12/2022 - 12:00
Front Med (Lausanne). 2022 Nov 17;9:988989. doi: 10.3389/fmed.2022.988989. eCollection 2022.NO ABSTRACTPMID:36465899 | PMC:PMC9712186 | DOI:10.3389/fmed.2022.988989

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