Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

Plasma-Like Culture Medium for the Study of Viruses

Wed, 14/12/2022 - 12:00
mBio. 2022 Dec 14:e0203522. doi: 10.1128/mbio.02035-22. Online ahead of print.NO ABSTRACTPMID:36515528 | DOI:10.1128/mbio.02035-22

Rich Organic Nitrogen Impacts Clavulanic Acid Biosynthesis through the Arginine Metabolic Pathway in Streptomyces clavuligerus F613-1

Wed, 14/12/2022 - 12:00
Microbiol Spectr. 2022 Dec 14:e0201722. doi: 10.1128/spectrum.02017-22. Online ahead of print.NO ABSTRACTPMID:36515504 | DOI:10.1128/spectrum.02017-22

Alginate oligosaccharide ameliorates azithromycin-induced gut microbiota disorder <em>via Bacteroides acidifaciens</em>-FAHFAs and <em>Bacteroides</em>-TCA cycle axes

Wed, 14/12/2022 - 12:00
Food Funct. 2022 Dec 14. doi: 10.1039/d2fo02812c. Online ahead of print.NO ABSTRACTPMID:36515227 | DOI:10.1039/d2fo02812c

Mechanistic study of salidroside on ovalbumin-induced asthmatic model mice based on untargeted metabolomics analysis

Wed, 14/12/2022 - 12:00
Food Funct. 2022 Dec 14. doi: 10.1039/d2fo02225g. Online ahead of print.NO ABSTRACTPMID:36515134 | DOI:10.1039/d2fo02225g

Shifting-corrected regularized regression for 1H NMR metabolomics identification and quantification

Wed, 14/12/2022 - 12:00
Biostatistics. 2022 Dec 12;24(1):140-160. doi: 10.1093/biostatistics/kxac015.NO ABSTRACTPMID:36514939 | DOI:10.1093/biostatistics/kxac015

Analysis of protective effects of <em>Rosa Roxburghii</em> Tratt fruit polyphenols on lipopolysaccharide-induced acute lung injury through network pharmacology and metabolomics

Wed, 14/12/2022 - 12:00
Food Sci Nutr. 2022 Aug 25;10(12):4258-4269. doi: 10.1002/fsn3.3019. eCollection 2022 Dec.NO ABSTRACTPMID:36514748 | PMC:PMC9731534 | DOI:10.1002/fsn3.3019

Genetic expression changes and pathologic findings associated with hyperhomocysteinemia in human autopsy brain tissue

Wed, 14/12/2022 - 12:00
Alzheimers Dement (N Y). 2022 Dec 8;8(1):e12368. doi: 10.1002/trc2.12368. eCollection 2022.NO ABSTRACTPMID:36514441 | PMC:PMC9732462 | DOI:10.1002/trc2.12368

Metabolomics of Extracellular Vesicles: A Future Promise of Multiple Clinical Applications

Wed, 14/12/2022 - 12:00
Int J Nanomedicine. 2022 Dec 7;17:6113-6129. doi: 10.2147/IJN.S390378. eCollection 2022.NO ABSTRACTPMID:36514377 | PMC:PMC9741837 | DOI:10.2147/IJN.S390378

A non-targeted metabolomics study on serum of occupational people exposed with nanometer titanium dioxide particles (TiO(2)-NPs)

Tue, 13/12/2022 - 12:00
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2022 Nov 20;40(11):813-820. doi: 10.3760/cma.j.cn121094-20210318-00158.NO ABSTRACTPMID:36510714 | DOI:10.3760/cma.j.cn121094-20210318-00158

High plasma concentrations of acyl-coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of ACBP

Tue, 13/12/2022 - 12:00
Aging Cell. 2022 Dec 12:e13751. doi: 10.1111/acel.13751. Online ahead of print.NO ABSTRACTPMID:36510662 | DOI:10.1111/acel.13751

Potential serum metabolites and long-chain noncoding RNA biomarkers for endometrial cancer tissue

Tue, 13/12/2022 - 12:00
J Obstet Gynaecol Res. 2022 Dec 12. doi: 10.1111/jog.15494. Online ahead of print.NO ABSTRACTPMID:36510632 | DOI:10.1111/jog.15494

Engineering isoprenoids production in metabolically versatile microbial host Pseudomonas putida

Mon, 12/12/2022 - 12:00
Biotechnol Biofuels Bioprod. 2022 Dec 12;15(1):137. doi: 10.1186/s13068-022-02235-6.NO ABSTRACTPMID:36510293 | DOI:10.1186/s13068-022-02235-6

Significant alterations of intestinal symbiotic microbiota induced by intraperitoneal vaccination mediate changes in intestinal metabolism of NEW Genetically Improved Farmed Tilapia (NEW GIFT, Oreochromis niloticus)

Mon, 12/12/2022 - 12:00
Microbiome. 2022 Dec 12;10(1):221. doi: 10.1186/s40168-022-01409-6.NO ABSTRACTPMID:36510260 | DOI:10.1186/s40168-022-01409-6

The community ecology perspective of omics data

Mon, 12/12/2022 - 12:00
Microbiome. 2022 Dec 13;10(1):225. doi: 10.1186/s40168-022-01423-8.NO ABSTRACTPMID:36510248 | DOI:10.1186/s40168-022-01423-8

Metabolic reprogramming and membrane glycan remodeling as potential drivers of zebrafish heart regeneration

Mon, 12/12/2022 - 12:00
Commun Biol. 2022 Dec 13;5(1):1365. doi: 10.1038/s42003-022-04328-2.NO ABSTRACTPMID:36509839 | DOI:10.1038/s42003-022-04328-2

Metabolites enhance innate resistance to human Mycobacterium tuberculosis infection

Mon, 12/12/2022 - 12:00
JCI Insight. 2022 Nov 22;7(22):e152357. doi: 10.1172/jci.insight.152357.NO ABSTRACTPMID:36509283 | DOI:10.1172/jci.insight.152357

Ginsenoside Rb1 protects against diabetes-associated metabolic disorders in Kkay mice by reshaping gut microbiota and fecal metabolic profiles

Mon, 12/12/2022 - 12:00
J Ethnopharmacol. 2022 Dec 9:115997. doi: 10.1016/j.jep.2022.115997. Online ahead of print.NO ABSTRACTPMID:36509256 | DOI:10.1016/j.jep.2022.115997

Improving flavor of summer Keemun black tea by solid-state fermentation using Cordyceps militaris revealed by LC/MS-based metabolomics and GC/MS analysis

Mon, 12/12/2022 - 12:00
Food Chem. 2022 Dec 9;407:135172. doi: 10.1016/j.foodchem.2022.135172. Online ahead of print.NO ABSTRACTPMID:36508871 | DOI:10.1016/j.foodchem.2022.135172

Integration of metabolomics and proteomics reveals the underlying hepatotoxic mechanism of perfluorooctane sulfonate (PFOS) and 6:2 chlorinated polyfluoroalkyl ether sulfonic acid (6:2 Cl-PFESA) in primary human hepatocytes

Mon, 12/12/2022 - 12:00
Ecotoxicol Environ Saf. 2022 Dec 9;249:114361. doi: 10.1016/j.ecoenv.2022.114361. Online ahead of print.NO ABSTRACTPMID:36508832 | DOI:10.1016/j.ecoenv.2022.114361

Effects of antimony stress on growth, structure, enzyme activity and metabolism of Nipponbare rice (Oryza sativa L.) roots

Mon, 12/12/2022 - 12:00
Ecotoxicol Environ Saf. 2022 Dec 9;249:114409. doi: 10.1016/j.ecoenv.2022.114409. Online ahead of print.NO ABSTRACTPMID:36508805 | DOI:10.1016/j.ecoenv.2022.114409

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