Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics

Mon, 12/12/2022 - 12:00
Front Pharmacol. 2022 Nov 23;13:1066244. doi: 10.3389/fphar.2022.1066244. eCollection 2022.NO ABSTRACTPMID:36506541 | PMC:PMC9727497 | DOI:10.3389/fphar.2022.1066244

Discovery of the key active compounds in Citri Reticulatae Pericarpium (<em>Citrus reticulata</em> "Chachi") and their therapeutic potential for the treatment of COVID-19 based on comparative metabolomics and network pharmacology

Mon, 12/12/2022 - 12:00
Front Pharmacol. 2022 Nov 23;13:1048926. doi: 10.3389/fphar.2022.1048926. eCollection 2022.NO ABSTRACTPMID:36506534 | PMC:PMC9727096 | DOI:10.3389/fphar.2022.1048926

Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury

Mon, 12/12/2022 - 12:00
Front Pharmacol. 2022 Nov 23;13:1043945. doi: 10.3389/fphar.2022.1043945. eCollection 2022.NO ABSTRACTPMID:36506525 | PMC:PMC9727196 | DOI:10.3389/fphar.2022.1043945

Serum and brain metabolomic study reveals the protective effects of Bai-Mi-Decoction on rats with ischemic stroke

Mon, 12/12/2022 - 12:00
Front Pharmacol. 2022 Nov 24;13:1005301. doi: 10.3389/fphar.2022.1005301. eCollection 2022.NO ABSTRACTPMID:36506507 | PMC:PMC9729534 | DOI:10.3389/fphar.2022.1005301

Association between lipid metabolism and cognitive function in patients with schizophrenia

Mon, 12/12/2022 - 12:00
Front Psychiatry. 2022 Nov 24;13:1013698. doi: 10.3389/fpsyt.2022.1013698. eCollection 2022.NO ABSTRACTPMID:36506447 | PMC:PMC9729695 | DOI:10.3389/fpsyt.2022.1013698

Applications of machine learning in metabolomics: Disease modeling and classification

Mon, 12/12/2022 - 12:00
Front Genet. 2022 Nov 24;13:1017340. doi: 10.3389/fgene.2022.1017340. eCollection 2022.NO ABSTRACTPMID:36506316 | PMC:PMC9730048 | DOI:10.3389/fgene.2022.1017340

Gut microbiome and fecal metabolic alteration in systemic lupus erythematosus patients with depression

Mon, 12/12/2022 - 12:00
Front Cell Infect Microbiol. 2022 Nov 25;12:1040211. doi: 10.3389/fcimb.2022.1040211. eCollection 2022.NO ABSTRACTPMID:36506019 | PMC:PMC9732533 | DOI:10.3389/fcimb.2022.1040211

FK506-binding protein, FKBP12, promotes serine utilization and negatively regulates threonine deaminase in fission yeast

Mon, 12/12/2022 - 12:00
iScience. 2022 Nov 24;25(12):105659. doi: 10.1016/j.isci.2022.105659. eCollection 2022 Dec 22.NO ABSTRACTPMID:36505930 | PMC:PMC9730122 | DOI:10.1016/j.isci.2022.105659

Plasma metabolic disturbances during pregnancy and postpartum in women with depression

Mon, 12/12/2022 - 12:00
iScience. 2022 Nov 24;25(12):105666. doi: 10.1016/j.isci.2022.105666. eCollection 2022 Dec 22.NO ABSTRACTPMID:36505921 | PMC:PMC9732390 | DOI:10.1016/j.isci.2022.105666

Multi-omics approach to identifying isoform variants as therapeutic targets in cancer patients

Mon, 12/12/2022 - 12:00
Front Oncol. 2022 Nov 24;12:1051487. doi: 10.3389/fonc.2022.1051487. eCollection 2022.NO ABSTRACTPMID:36505834 | PMC:PMC9730332 | DOI:10.3389/fonc.2022.1051487

Novel therapeutic approach to slow down the inflammatory cascade in acute/subacute spinal cord injury: Early immune therapy with lipopolysaccharide enhanced neuroprotective effect of combinational therapy of granulocyte colony-stimulating factor and...

Mon, 12/12/2022 - 12:00
Front Cell Neurosci. 2022 Nov 23;16:993019. doi: 10.3389/fncel.2022.993019. eCollection 2022.NO ABSTRACTPMID:36505513 | PMC:PMC9727083 | DOI:10.3389/fncel.2022.993019

Gamma-glutamyl-leucine levels are causally associated with elevated cardio-metabolic risks

Mon, 12/12/2022 - 12:00
Front Nutr. 2022 Nov 24;9:936220. doi: 10.3389/fnut.2022.936220. eCollection 2022.NO ABSTRACTPMID:36505257 | PMC:PMC9729530 | DOI:10.3389/fnut.2022.936220

3-Bromopyruvate inhibits pancreatic tumor growth by stalling glycolysis, and dismantling mitochondria in a syngeneic mouse model

Mon, 12/12/2022 - 12:00
Am J Cancer Res. 2022 Nov 15;12(11):4977-4987. eCollection 2022.NO ABSTRACTPMID:36504891 | PMC:PMC9729896

A fungus (<em>Trametes pubescens</em>) resists cadmium toxicity by rewiring nitrogen metabolism and enhancing energy metabolism

Mon, 12/12/2022 - 12:00
Front Microbiol. 2022 Nov 21;13:1040579. doi: 10.3389/fmicb.2022.1040579. eCollection 2022.NO ABSTRACTPMID:36504813 | PMC:PMC9733723 | DOI:10.3389/fmicb.2022.1040579

UPLC-TOF/MS-based metabolomics reveals the chemical changes and <em>in vitro</em> biological effects in fermentation of white ginseng by four probiotics

Mon, 12/12/2022 - 12:00
Front Microbiol. 2022 Nov 24;13:1022200. doi: 10.3389/fmicb.2022.1022200. eCollection 2022.NO ABSTRACTPMID:36504795 | PMC:PMC9729340 | DOI:10.3389/fmicb.2022.1022200

<em>Epichloë bromicola</em> from wild barley improves salt-tolerance of cultivated barley by altering physiological responses to salt stress

Mon, 12/12/2022 - 12:00
Front Microbiol. 2022 Nov 24;13:1044735. doi: 10.3389/fmicb.2022.1044735. eCollection 2022.NO ABSTRACTPMID:36504776 | PMC:PMC9730248 | DOI:10.3389/fmicb.2022.1044735

Effects of black soldier fly larvae as protein or fat sources on apparent nutrient digestibility, fecal microbiota, and metabolic profiles in beagle dogs

Mon, 12/12/2022 - 12:00
Front Microbiol. 2022 Nov 25;13:1044986. doi: 10.3389/fmicb.2022.1044986. eCollection 2022.NO ABSTRACTPMID:36504773 | PMC:PMC9733673 | DOI:10.3389/fmicb.2022.1044986

The effects of elemene emulsion injection on rat fecal microbiota and metabolites: Evidence from metagenomic exploration and liquid chromatography-mass spectrometry

Mon, 12/12/2022 - 12:00
Front Microbiol. 2022 Nov 24;13:913461. doi: 10.3389/fmicb.2022.913461. eCollection 2022.NO ABSTRACTPMID:36504762 | PMC:PMC9730252 | DOI:10.3389/fmicb.2022.913461

Identification of metabolic fingerprints in severe obstructive sleep apnea using gas chromatography-Mass spectrometry

Mon, 12/12/2022 - 12:00
Front Mol Biosci. 2022 Nov 21;9:1026848. doi: 10.3389/fmolb.2022.1026848. eCollection 2022.NO ABSTRACTPMID:36504723 | PMC:PMC9732946 | DOI:10.3389/fmolb.2022.1026848

Untargeted metabolomics screening reveals unique secondary metabolite production from <em>Alternaria</em> section <em>Alternaria</em>

Mon, 12/12/2022 - 12:00
Front Mol Biosci. 2022 Nov 24;9:1038299. doi: 10.3389/fmolb.2022.1038299. eCollection 2022.NO ABSTRACTPMID:36504718 | PMC:PMC9731300 | DOI:10.3389/fmolb.2022.1038299

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