Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

PubMed

Editorial: Multi-omics: Trends and applications in clinical research

Mon, 12/12/2022 - 12:00
Front Mol Biosci. 2022 Nov 24;9:994239. doi: 10.3389/fmolb.2022.994239. eCollection 2022.NO ABSTRACTPMID:36504715 | PMC:PMC9731206 | DOI:10.3389/fmolb.2022.994239

Increasing quantitation in spatial single-cell metabolomics by using fluorescence as ground truth

Mon, 12/12/2022 - 12:00
Front Mol Biosci. 2022 Nov 24;9:1021889. doi: 10.3389/fmolb.2022.1021889. eCollection 2022.NO ABSTRACTPMID:36504713 | PMC:PMC9730270 | DOI:10.3389/fmolb.2022.1021889

Limited carbon cycling due to high-pressure effects on the deep-sea microbiome

Mon, 12/12/2022 - 12:00
Nat Geosci. 2022;15(12):1041-1047. doi: 10.1038/s41561-022-01081-3. Epub 2022 Nov 28.NO ABSTRACTPMID:36504693 | PMC:PMC9726642 | DOI:10.1038/s41561-022-01081-3

Sex as a biological variable in determining the metabolic changes influencing acute ischemic stroke outcomes-Where is the data: A systematic review

Mon, 12/12/2022 - 12:00
Front Neurol. 2022 Nov 24;13:1026431. doi: 10.3389/fneur.2022.1026431. eCollection 2022.NO ABSTRACTPMID:36504643 | PMC:PMC9729945 | DOI:10.3389/fneur.2022.1026431

ST3GAL5-catalyzed gangliosides inhibit TGF-β-induced epithelial-mesenchymal transition via TβRI degradation

Mon, 12/12/2022 - 12:00
EMBO J. 2022 Dec 12:e110553. doi: 10.15252/embj.2021110553. Online ahead of print.NO ABSTRACTPMID:36504224 | DOI:10.15252/embj.2021110553

Isolation of a novel missense mutation in insulin receptor as a spontaneous revertant of ImpL2 mutant in Drosophila

Mon, 12/12/2022 - 12:00
Development. 2022 Dec 9:dev.201248. doi: 10.1242/dev.201248. Online ahead of print.NO ABSTRACTPMID:36504086 | DOI:10.1242/dev.201248

Integrated transcriptome and metabolome analysis reveals molecular responses of spider to single and combined high temperature and drought stress

Mon, 12/12/2022 - 12:00
Environ Pollut. 2022 Nov 26;317:120763. doi: 10.1016/j.envpol.2022.120763. Online ahead of print.NO ABSTRACTPMID:36503821 | DOI:10.1016/j.envpol.2022.120763

Ammonia-induced oxidative stress triggered proinflammatory response and apoptosis in pig lungs

Mon, 12/12/2022 - 12:00
J Environ Sci (China). 2023 Apr;126:683-696. doi: 10.1016/j.jes.2022.05.005. Epub 2022 May 19.NO ABSTRACTPMID:36503793 | DOI:10.1016/j.jes.2022.05.005

Gut microbiota alterations in stable outpatients with schizophrenia: Findings from a case-control study

Mon, 12/12/2022 - 12:00
Acta Neuropsychiatr. 2022 Dec 12:1-23. doi: 10.1017/neu.2022.38. Online ahead of print.NO ABSTRACTPMID:36503629 | DOI:10.1017/neu.2022.38

Acidic ascites inhibits ovarian cancer cell proliferation and correlates with the metabolomic, lipidomic and inflammatory phenotype of human patients

Mon, 12/12/2022 - 12:00
J Transl Med. 2022 Dec 12;20(1):581. doi: 10.1186/s12967-022-03763-3.NO ABSTRACTPMID:36503580 | DOI:10.1186/s12967-022-03763-3

Integrated multi-omics of the gastrointestinal microbiome and ruminant host reveals metabolic adaptation underlying early life development

Mon, 12/12/2022 - 12:00
Microbiome. 2022 Dec 12;10(1):222. doi: 10.1186/s40168-022-01396-8.NO ABSTRACTPMID:36503572 | DOI:10.1186/s40168-022-01396-8

Analysis of correlations between gut microbiota, stool short chain fatty acids, calprotectin and cardiometabolic risk factors in postmenopausal women with obesity: a cross-sectional study

Mon, 12/12/2022 - 12:00
J Transl Med. 2022 Dec 12;20(1):585. doi: 10.1186/s12967-022-03801-0.NO ABSTRACTPMID:36503483 | DOI:10.1186/s12967-022-03801-0

Integrated Metabonomic Study on the Relationship between Medicinal Properties and Efficacy of <em>Rehmanniae</em> Radix

Mon, 12/12/2022 - 12:00
Am J Chin Med. 2022 Dec 12:1-19. doi: 10.1142/S0192415X23500106. Online ahead of print.NO ABSTRACTPMID:36503428 | DOI:10.1142/S0192415X23500106

DiviK: divisive intelligent K-means for hands-free unsupervised clustering in big biological data

Mon, 12/12/2022 - 12:00
BMC Bioinformatics. 2022 Dec 12;23(1):538. doi: 10.1186/s12859-022-05093-z.NO ABSTRACTPMID:36503372 | DOI:10.1186/s12859-022-05093-z

Analyses of widely targeted metabolic profiling reveals mechanisms of metabolomic variations during Tibetan sheep (Ovis aries) testis development

Sun, 11/12/2022 - 12:00
Theriogenology. 2022 Nov 28;197:116-126. doi: 10.1016/j.theriogenology.2022.11.041. Online ahead of print.NO ABSTRACTPMID:36502589 | DOI:10.1016/j.theriogenology.2022.11.041

Transcriptomics and metabolomics together reveal the underlying mechanism of heroin hepatotoxicity

Sun, 11/12/2022 - 12:00
Toxicology. 2022 Dec 8;483:153393. doi: 10.1016/j.tox.2022.153393. Online ahead of print.NO ABSTRACTPMID:36502556 | DOI:10.1016/j.tox.2022.153393

Study on Flavonoids and Bioactivity Features of Pericarp of <em>Citrus reticulata</em> "Chachi" at Different Harvest Periods

Sun, 11/12/2022 - 12:00
Plants (Basel). 2022 Dec 5;11(23):3390. doi: 10.3390/plants11233390.NO ABSTRACTPMID:36501428 | DOI:10.3390/plants11233390

<em>Citrus reticulata</em> Leaves Essential Oil as an Antiaging Agent: A Comparative Study between Different Cultivars and Correlation with Their Chemical Compositions

Sun, 11/12/2022 - 12:00
Plants (Basel). 2022 Dec 1;11(23):3335. doi: 10.3390/plants11233335.NO ABSTRACTPMID:36501374 | DOI:10.3390/plants11233335

Metabolomics Approach to Characterize Green Olive Leaf Extracts Classified Based on Variety and Season

Sun, 11/12/2022 - 12:00
Plants (Basel). 2022 Dec 1;11(23):3321. doi: 10.3390/plants11233321.NO ABSTRACTPMID:36501360 | DOI:10.3390/plants11233321

The Antimethanogenic Potentials of Plant Extracts: Their Yields and Phytochemical Compositions as Affected by Extractive Solvents

Sun, 11/12/2022 - 12:00
Plants (Basel). 2022 Nov 29;11(23):3296. doi: 10.3390/plants11233296.NO ABSTRACTPMID:36501339 | DOI:10.3390/plants11233296

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