Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

Our research involves applying mass spectrometry-based technologies to perform molecular phenotyping at the population level. This work entails the development of both LC/MS and GC/MS methods for the quantification of lipids and other metabolites. A major focus of the lab also centers on developing the associated bioinformatics approaches including pathway analysis and network construction as well as multivariate statistical methods for integration of 'omics-based data structures.

Lab news

Postdoc Position available

We are now recuriting a Post-doctoral Researcher in functional metabolomics of lipid mediators in respiratory disease.

New paper published

New lab paper suggests that linoleic acid-derived lipids in BAL fluid may indicate the transition from healthy smoker to COPD in a female-dominated sub-phenotype. 

New sample manager

The lab has just purchased the Extrahera automation system from Biotage for solid phase extraction (SPE)

MetaboNews Interview

Craig Wheelock was interviewed in the recent issue of MetaboNews to share his thoughts on metabolomics