Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

Years

Publications

M Mittal, M Hasan, N Balagunaseelana, A Fauland, C Wheelock, O Rådmark, JZ Haeggström, and A Rinaldo-Matthis, 2017. Investigation of calcium-dependent activity and conformational dynamics of zebra fish 12-lipoxygenase. Biochem Biophys Acta. 1861(8):2099-2111.
S Naz, J Kolmert, M Xing, SN Reinke, MA Kamleh, S Snowden, T Heyder, B Levänen, DJ Erle, M Sköld, ÅM Wheelock, and CE Wheelock, 2017. Metabolomics analysis identifies gender-associated metabotypes of oxidative stress and the autotaxin-lysoPA axis in COPD. European Respiratory Journal, in press
SN Reinke, H Gallart-Ayala, C Gomez, A Checa, A Fauland, S Naz, MA Kamleh, R Djurvanovic, T Hinks, and CE Wheelock, 2017. Metabolomics analysis identifies different metabotypes of asthma severity. European Respiratory Journal, 49:1601740.
MH Petri, A Laguna-Fernandez, H Arnardottir, CE Wheelock, M Perretti, GK Hansson, M Bäck. Aspirin-triggered lipoxin inhibits atherosclerosis progression in ApoE-/- mice. British Journal of Pharmacology. 2017 Jan 10. doi: 10.1111/bph.13707
Checa, H Idborg, A Zandian, DG Sar, I Surowiec, J Trygg, E Svenungsson, PJ Jakobsson, P Nilsson, I Gunnarson, and CE Wheelock, 2016. Dysregulations in circulating sphingolipids associate with disease activity indices in female patients with systemic lupus erythematous: a cross-sectional study. Lupus, in press.
D González-Peña, A Checa, B de Ancosa, CE Wheelock, C Sánchez-Moreno, 2016. New insights into the effects of onion consumption on lipid mediators using a diet-induced model of hypercholesterolemia. Redox Biology, 11:205-212.
O Kövamees, A Shemyakin, A Checa, CE Wheelock, JO Lundberg, CG Östenson, J Pernow, 2016. Arginase inhibition improves microvascular endothelial function in patients with type 2 diabetes mellitus. Journal of Clinical Endocrinology and Metabolism, 101(11):3952-3958.
M Hezel, M Peleli, M Liu, C Zollbrecht, BL Jensen, A Checa, A Giulietti, CE Wheelock, JO Lundberg, E Weitzberg and M Carlström, 2016. Dietary nitrate improves age-related hypertension and metabolic abnormalities via modulation of angiotensin II receptor signaling and inhibition of superoxide generation. Free Radical and Biology Medicine. 26(99):87-98.
D Paquin-Proulx, A Gibbs, S Bächle, A Checa, A Introini, E Leeansyah, CE Wheelock, DF Nixon, K Broliden, A Tjernlund, M Moll, and JK Sandberg, 2016. Innate iNKT cell recognition of HIV-1 infected dendritic cells is an early detection mechanism targeted by viral immune evasion. Journal of Immunology. 197(5):1843-51.
T Yang, C Zollbrecht, ME Winerdal, Z Zhuge, XM Zhang, N Terrando, A Checa, J Sällström, CE Wheelock, O Winqvist, RA Harris, E Larsson, AE Persson, BB Fredholm, M Carlström, 2016. Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension. Journal of the American Heart Association, 18;5(7). pii: e003868.
M Carlström, C Cananau, A Checa, K Wide, L Sartz, A Svensson, CE Wheelock, S Westphal, Z Békássy, P Bárány, JO Lundberg, S Hansson, E Weitzberg, RT Krmar, 2016. Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia. Nitric Oxide, 58:1-9.
D Balgoma, M Yang, M Sjödin, SG Snowden, R Karimi, B Levänen, H Merikallio, R Kaarteenaho, L Palmberg, K Larsson, DJ Erle, SE Dahlén, B Dahlén, CM Sköld, ÅM Wheelock, and CE Wheelock, 2016. Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD. European Respiratory Journal, 47(6):1645-56.
K Jandl, E Stacher, Z Bálint, EM Sturm, J Maric, M Peinhaupt, P Luschnig, I Aringer, A Fauland, V Konya, SE Dahlen, CE Wheelock, D Kratky, A Olschewski, G Marsche, R Schuligoi, A Heinemann, 2016. Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung. J Allergy Clin Immunol. 137(3):833-43.
RB Frei, P Luschnig, GP Parzmair, M Peinhaupt, S Schranz, A Fauland, CE Wheelock, A Heinemann, EM Sturm, 2016. Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen-induced pulmonary inflammation in mice. Allergy. Feb 6. doi: 10.1111/all.12858.
I Roci, H Gallart-Ayala, A Schmidt, J Watrous, M Jain, CE Wheelock, R Nilsson, 2016. Metabolite profiling and stable isotope tracing in sorted subpopulations of mammalian cells. Analytical Chemistry. 88(5):2707-13.
L Perisic, S Aldi, Y Sun, L Folkersen, A Razuvaev, J Roy, M Lengquist, S Åkesson, CE Wheelock, L Maegdefessel, A Gabrielsen, J Odeberg, G Hansson, G Paulsson-Berne, U Hedin, 2016. Gene expression signatures, pathways and networks in carotid atherosclerosis. Journal of Internal Medicine, 279(3):293-308.
A Checa, T Holm, MOD Sjödin, SN Reinke, J Alm, A Scheynius, CE Wheelock, 2015. Lipid mediator profile in vernix caseosa reflects skin barrier development. Scientific Reports 5:15740 | DOI:10.1038/srep15740.
ML Oliveira, FL D'Alexandri, G Pugliesi, V Van Hoeck, FS Mesquita, CM Membrive, JA Negrão, CE Wheelock, M Binelli, 2015. Peri-ovulatory endocrine regulation of the prostanoid pathways in the bovine uterus at early dioestrus. Reproduction Fertility and Development Oct 14. doi: 10.1071/RD15269.
A Checa, N Xu, DG Sar, JZ Haeggström, M Ståhle, CE Wheelock, 2015. Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment. Scientific Reports. 5:12017 | DOI: 10.1038/srep12017.
JR Bood, BM Sundblad, I Delin, M Sjödin, KS Larsson, SD Anderson, CE Wheelock, SE Dahlen, B Dahlen, 2015. Urinary excretion of lipid mediators in response to repeated eucapnic voluntary hyperpnea in asthmatics. Journal of Applied Physiology. In press. doi: 10.1152/japplphysiol.00301.2015

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