Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

Years

Publications

MA Lankinen, M Vaittinen, A Fauland, B Shimizu, CE Wheelock, M Laakso, U Schwab, J Pihlajamäki, 2019. Lipidomic and inflammatory response to dietary linoleic acid depends on the FADS1 genotype in a genotype based clinical trial. American Journal of Clinical Nutrition, 108:1–11.
J Maric, A Ravindran, L Mazzurana, A Van Acker, A Rao, M Ekoff, D Thomas, A Fauland, G Nilson, CE Wheelock, SE Dahlen, N Ferreiros Bouzas, G Geisslinger, D Friberg, A Heinemann, V Konya, J Mjösberg, 2018. Cytokine-induced endogenous production of PGD2 is essential for human ILC2 activation. Journal of Allergy and Clinical Immunology, pii: S0091-6749(18)32774-X.
M Dyszynski, M Vesterlund, AC Björklund, V Zachardias, J Janssen, H Gallart-Ayala, CE Wheelock, J Lehtiö, D Grandér, K Pokrovskaja Tamm, R Nilsson, 2018. Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment. Cell Death and Disease, 9(9):846.
M Sjödin, A Checa, M Yang, SE Dahlén, ÅM Wheelock, J Grunewald, CE Wheelock, 2018. Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis. Respiratory Research, 19(1):236.
A Lukic, C Wahlund, C Gomez, D Brodin, B Samuelsson, CE Wheelock, S Gabrielsson, Olof Rådmark, 2018. Exosomes from lung cancer pleura exudates promote cancer cell migration and survival via CysLT1. Cancer Letters. 444:1-8.
N Lazarinis, J Bood, C Gomez, J Kolmert, AS Lantz, P Gyllfors, A Davis, CE Wheelock, SE Dahlén, B Dahlén, 2018. The CysLT1 receptor mediates bronchoconstriction and mast cell activation induced by inhalation of leukotriene E4 in subjects with asthma. Journal of Allergy and Clinical Immunology, 142(4):1080-1089.
CX Li, CE Wheelock CE, CM Sköld, ÅM Wheelock, 2018. Integration of multi-omics datasets enables molecular classification of COPD. European Respiratory Journal. 51(5).
B Burla, M Arita, M Arita, AK Bendt, A Cazenave-Gassiot, EA Dennis, K Ekroos, X Han, K Ikeda, G Liebisch, MK Lin, T Ping Loh, PJ Meikle, M Orešič, O Quehenberger, A Shevchenko, F Torta, MJO Wakelam, CE Wheelock, and MR Wenk, 2018. Mass spectrometry-based lipidomics of human blood plasma - a community-initiated position paper aimed at developing generally accepted guidelines. 59(10):2001-2017.
A Mazein, RG Knowles, I Adcock, KF Chung, CE Wheelock, AH Maitland-van der Zee, PJ Sterk, C Auffray, 2018. AsthmaMap: An expert-driven computational representation of disease mechanisms; AsthmaMap Project Team. Clinical Experimental Allergy. 48(8):916-918.
M Dyszynski, M Vesterlund, AC Björklund, V Zachardias, J Janssen, H Gallart-Ayala, CE Wheelock, J Lehtiö, D Grandér, K Pokrovskaja Tamm, R Nilsson, 2018. Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment. Cell Death and Disease, 9(9):846.
A Mahdi, O Kövamees, A Checa, CE Wheelock, M von Heijne, M Alvarsson, J Pernow, 2018. Arginase inhibition improves endothelial function in patients with type 2 diabetes mellitus despite intensive glucose lowering therapy. Journal of Internal Medicine. 284(4):388-398.
SN Reinke, B Galindo-Prieto, T Skotare, DI Broadhurst, A Singhania, D Horowitz, R Djukanović, TSC Hinks, P Geladi, J Trygg, CE Wheelock, 2018. OnPLS-based multi-block data integration: a multivariate approach to interrogating biological interactions in asthma. Analytical Chemistry, in press.
D Fuchs, M Hamberg, CM Sköld, ÅM Wheelock, CE Wheelock, 2018. An LC-MS/MS workflow to characterize 16 regio- and stereoisomeric trihydroxyoctadecenoic acids (TriHOMEs). Journal Lipid Research. pii: jlr.D087429.
J Kolmert, A Fauland, D Fuchs, J Säfholm, C Gomez, M Adner, SE Dahlén, CE Wheelock, 2018. Lipid mediator quantification in isolated human and guinea pig airways – an expanded approach for respiratory research. Analytical Chemistry, 90(17):10239-10248.
R Chaleckis, I Meister, P Zhang, CE Wheelock, 2018. Challenges, progress and promises of metabolite annotation for LC–MS-based metabolomics. Current Opinion in Biotechnology, edited by Saulius Klimasauskas and Linas Mazutis. 55:44-50.
E Daskalaki, NJ Pillon, A Krook, CE Wheelock, A Checa, 2018. The influence of culture media upon observed cell secretome metabolite profiles: the balance between cell viability and data interpretability. Analytica Chimica Acta, 1037:338-350.
A Checa, A Malmqvist, L Flyckt, L Schwieler, M Samuelsson, E Skogh, S Cervenka, ML Dahl, F Piehl, Karolinska Schizophrenia Project (KaSP) consortium, S Erhardt, CE Wheelock, 2018. Intrathecal sphingolipids associate with disease severity in first episode psychosis patients. Schizophrenia Research, 199:438-441.
R Emma, AT Bansal, J Kolmert, CE Wheelock, SE Dahlén, MJ Loza, B De Meulder, D Lefaudeux, C Auffray, B Dahlén, PS Bakke, P Chanez, I Horvath, A Chaiboonchoe, H Ahmed, S Ballereau, C Rossios, KF Chung, P Montuschi, SJ Fowler, IM Adcock, AD Postle, A Rowe, PJ Sterk, R Djukanovic; the U-BIOPRED Study Group, 2018. Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort. PLoS One, 13(9):e0203874.
E Garreta-Lara, A Checa, D Fuchs, R Tauler, S Lacorte, CE Wheelock, C Barata, 2018. Effect of psychiatric drugs on Daphnia magna oxylipin profiles. Science of the Total Environment. 644:1101–1109.
AC Araujo, CE Wheelock, JZ Haeggström, 2018. The eicosanoids, redox regulated lipid mediators in immunometabolic disorders. Antioxidants and Redox Signaling. 29(3):275-296.

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