Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

Years

Publications

J Kolmert, C Gómez, D Balgoma, M Sjödin, M Eriksson, M Mikus, J-O Thörngren; AJ James, A Sousa, P Bakke, H Bisgaard, FK Chung, M Caruso, P Chanez, A D’Amico, SJ Fowler, T Geiser, P Howarth, I Horváth, N Krug, P Montuschi, J Musial, T Sandström, DE Shaw, I Pandis, R Knowles, R Djukanovic, B Dahlén, PJ Sterk, SE Dahlén, CE Wheelock, on behalf of the U-BIOPRED Study Group, 2020. Increased urinary leukotriene E4 and prostaglandin D2 metabolites in severe asthma and type-2 inflammation. American Journal of Respiratory and Critical Care Medicine, doi: 10.1164/rccm.201909-1869OC.
I Tada, R Chaleckis, H Tsugawa, I Meister, P Zhang, N Lazarinis, B Dahlén, CE Wheelock, M Arita, 2020. Correlation-Based Deconvolution (CorrDec) To Generate High-Quality MS2 Spectra from Data-Independent Acquisition in Multisample Studies. Analytical Chemistry. 92(16):11310-11317.
NZ Kermani, M Saqi, P Agapow, S Pavlidis, C Kuo, KS Tan, S Mumby, K Sun, M Loza, F Baribaud, AR Sousa, J Riley, ÅM Wheelock, CE Wheelock, B De Meulder, J Schofield, S Sánchez-Ovando, J Louise Simpson, KJ Baines, PA Wark, C Auffray, SE Dahlen, PJ Sterk, R Djukanovic, IM Adcock, YK Guo, KF Chung; U-BIOPRED project team, 2020. Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics. Allergy. doi: 10.1111/all.14573.
SH Møller, M Mellergaard, M Madsen, AV Bermejo, SD Jepsen, MH Hansen, RI Høgh, BI Aldana, C Desler, LJ Rasmussen, EG Sustarsic, Z Gerhart-Hines, E Daskalaki, CE Wheelock, TK Hiron, D Lin, CA O'Callaghan, HH Wandall, L Andresen, S Skov, 2020. Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells. Frontiers in Immunology. 11:1968.
YA Ambaw , D Fuchs, M Raida, NT Mazengia, F Torta, CE Wheelock, MR Wenk, L Tong L, 2020. Changes of tear lipid mediators after eyelid warming or thermopulsation treatment for meibomian gland dysfunction. Prostaglandins and Other Lipid Mediators. 151:106474.
T Meuronen, M Lankinen, A Fauland, B Shimizu, V de Mello, D Laaksonen, CE Wheelock, A Erkkilä, U Schwab, 2020. Intake of Camelina Sativa Oil and Fatty Fish Alter The Plasma Lipid Mediator Profile in Subjects with Impaired Glucose Metabolism – A Randomized Controlled Trial. Prostaglandins, Leukotrienes and Essential Fatty Acids, 159:102143.
G Artiach, M Carracedo, O Plunde, CE Wheelock, S Thul, P Sjövall, A Franco-Cereceda, A Laguna-Fernandez, H Arnardottir, M Bäck, 2020. Omega-3 Polyunsaturated Fatty Acids Decrease Aortic Valve Disease Through the Resolvin E1 and ChemR23 Axis. Circulation. 142(8):776-789.
CE Wheelock and SM Rappaport, 2020. The role of gene–environment interactions in lung disease: the urgent need for the exposome. European Respiratory Journal 55:1902064.
P Brinkman, W Ahmed, C Gómez, HH Knobel, H Weda, TJ Vink, TM Nijsen, CE Wheelock, SE Dahlen, P Montuschi, RG Knowles, SJ Vijverberg, AH Maitland-van der Zee, PJ Sterk, SJ Fowler, on behalf of the U-BIOPRED consortium, 2019. Exhaled Volatile Organic Compounds as Markers for Medication Use in Asthma. European Respiratory Journal, pii: 1900544.
P Zhang, M Arora, R Chaleckis, T Isobe, M Jain, I Meister, E Melén, M Perzanowski, F Torta, M Wenk and CE Wheelock, 2019. Tackling the Complexity of the Exposome: Considerations from the Gunma University Initiative for Advanced Research (GIAR) Exposome Symposium. Metabolites, 9(6). pii: E106.
LM Petrick, C Schiffman, WMB Edmands, Y Yano, K Perttula, T Whitehead, C Metayerd, CE Wheelock, M Arora, H Grigoryan, H Carlsson, S Dudoit and SM Rappaport, 2019. Metabolomics of neonatal blood spots reveal distinct phenotypes of pediatric acute lymphoblastic leukemia and potential effects of early-life nutrition. Cancer Letters, 452:71-78.
SH Chu, M Huang, RS Kelly, E Benedetti, J Siddiqui, OA Zeleznik, A Pereira, D Herrington, CE Wheelock, J Krumsiek, M McGeachie, SC Moore, P Kraft, E Mathé and J Lasky-Su, on behalf of the Consortium of Metabolomics Studies Statistics Working Group, 2019. Integration of Metabolomic and Other Omics Data in Population Based Study Designs: An Epidemiological Perspective. Metabolites. 9(6). pii: E117.
F Bergqvist, E Ossipova, H Idborg, J Raouf, A Checa, K Englund, P Englund, PE Khoonsari, K Kultima, CE Wheelock, M Korotkova, PJ Jakobsson, 2019. Inhibition of mPGES-1 or COX-2 Results in Different Proteomic and Lipidomic Profiles in A549 Lung Cancer Cells Frontiers in Pharmacology, 10:636.
H Idborg, A Zandian, E Ossipova, E Wigren, C Preger, F Mobarrez, A Checa, A Sohrabian, J Rönnelid, G Grosso, M Kvarnström, A Larsson, CE Wheelock, K Kultima, H Persson, S Gräslund, I Gunnarsson, P Nilsson, E Svenungsson, PJ Jakobsson, 2019. Circulating levels of Interferon Regulatory Factor-5 associates to subgroups of Systemic Lupus Erythematosus patient. Frontiers in Immunology, 10:1029.
LA Mortensen, C Bistrup, J Stubbe, M Carlström, A Checa, CE Wheelock, Y Palarasah EM Bladbjerg, HC Thiesson, BL Jensen, 2019. Effect of spironolactone for one year on endothelial function and vascular inflammation biomarkers in renal transplant recipients. American Journal of Physiology-Renal Physiology, 317(3):F529-F539.
KE Carlström, E Ewing, M Granqvist, A Gyllenberg, S Aeinehband, SL Enoksson, A Checa, TVS Badam, J Huang, D Gomez-Cabrero, M Gustafsson, FAl Nimer, CE Wheelock, I Kockum, T Olsson, M Jagodic and F Piehl, 2019. Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis is linked with ROS in monocytes. Nature Communications. 10(1):3081.
S Rad Pour, H Morikawa, NA Kiani, M Yang, A Azimi, G Shafi, M Shang, R Baumgartner, DFJ Ketelhuth, MA Kamleh, CE Wheelock, A Lundqvist, J Hansson, and J Tegnér, 2019. Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma. Scientific Reports. 9(1):12150.
C Gómez, C Gonzalez-Riano, C Barbas, J Kolmert, M Hyung Ryu, C Carlsten, SE Dahlén, CE Wheelock, 2019. Quantitative metabolic profiling of urinary eicosanoids for clinical phenotyping. Journal of Lipid Research. 60(6):1164-1173.
MA Lankinen, M Vaittinen, A Fauland, B Shimizu, CE Wheelock, M Laakso, U Schwab, J Pihlajamäki, 2019. Lipidomic and inflammatory response to dietary linoleic acid depends on the FADS1 genotype in a genotype based clinical trial. American Journal of Clinical Nutrition, 108:1–11.
J Maric, A Ravindran, L Mazzurana, A Van Acker, A Rao, M Ekoff, D Thomas, A Fauland, G Nilson, CE Wheelock, SE Dahlen, N Ferreiros Bouzas, G Geisslinger, D Friberg, A Heinemann, V Konya, J Mjösberg, 2018. Cytokine-induced endogenous production of PGD2 is essential for human ILC2 activation. Journal of Allergy and Clinical Immunology, pii: S0091-6749(18)32774-X.

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