P Zhang, C Carlsten, R Chaleckis, K Hanhineva, M Huang, T Isobe, VM Koistinen, I Meister, S Papazian, K Sdougko, H Xie, JW Martin, SM Rappaport, H Tsugawa, DI Walker, TJ Woodruff, RO Wright, CE Wheelock, 2021. Defining the Scope of Exposome Studies and Research Needs from a Multidisciplinary Perspective. Environmental Science & Technology Letters. 8(10):839-852.
R Abdalkader, R Chaleckis, I Meister, P Zhang, CE Wheelock, KI Kamei, 2020. Untargeted LC-MS metabolomics for the analysis of micro-scaled extracellular metabolites from hepatocytes. Analytical Science. 37(7):1049-1052.
J Liu, J Kolmert, J Safholm, AK Johnsson, J Zurita, CE Wheelock, SE Dahlen, G Nilsson, M Adner, 2021. Distinct effects of antigen and Compound 48/80 in the guinea pig trachea. Allergy. 76(7):2270-2273.
FH Alahmadi, AJ Simpson, C Gomez, M Ericsson, JO Thorngren, C Wheelock, DE Shaw, LJ Fleming, G Roberts, J Riley, S Bates, AR Sousa, R Knowles, AT Bansal, J Corfield, I Pandis, K Sun, PS Bakke, M Caruso, P Chanez, B Dahlen, I Horvath, N Krug, P Montuschi, F Singer, S Wagers, IM Adcock, R Djukanovic, KF Chung, PJ Sterk, SE Dahlen, SJ Fowler, and the U-BIOPRED Study Group, 2021. Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort. Chest. 160(1):53-64.
R Abdalkader, R Chaleckis, CE Wheelock, K Kamei, 2021. Spatiotemporal determination of metabolite activities in the corneal epithelium on a chip. Experimental Eye Research. 209:108646
A Alhamdow, A Zettergren, I Kull, J Hallberg, N Andersson, S Ekström, M Berglund, CE Wheelock, YJ Essig, AM Krais, A Georgelis, CH Lindh, E Melén, A Bergström, 2021. Low-level polycyclic aromatic hydrocarbon exposure is associated with reduced lung function in young adulthood. Environmental Research. 197:111169.
N Akawi, A Checa, AS Antonopoulos, I Akoumianakis, E Daskalaki, CP Kotanidis, H Kondo, K Lee, D Yesilyurt, I Badi, M Polkinghorne, N Akbar, J Lundgren, S Chuaiphichai, R Choudhury, S Neubauer, KM Channon, SS Torekov, CE Wheelock*, Charalambos Antoniades*, 2021. Fat-Secreted Ceramides Regulate Vascular Redox State and Influence Outcomes in Patients with Cardiovascular Disease. Journal of American College of Cardiology. 77(20):2494-2513.
AK Johnsson, E Ronnberg, D Fuchs, J Kolmert, J Safholm, HE Claesson, M Hamberg, CE Wheelock, G Nilsson, SE Dahlen, 2021. COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells. Biochim Biophys Acta Mol Cell Biol Lipids. 1866(5):158886.
J Kolmert, SE Dahlen, and CE Wheelock, 2021. Reply to Thomson: Exposure to Active and Passive Tobacco Smoke on Urinary Eicosanoid Metabolites in Type 2 Asthma. American Journal of Respiratory and Critical Care Medicine. 203(9):1204-1205.
YE Badi, AB Pavel, S Pavlidis, JH Riley, S Bates, NZ Kermani, R Knowles, J Kolmert, CE Wheelock, S Worsley, M Uddin, K Alving, PS Bakke, A Behndig, M Caruso, P Chanez, LJ Fleming, SJ Fowler, U Frey, P Howarth, I Horváth, N Krug, AH Maitland-van der Zee, P Montuschi, G Roberts, M Sanak, DE Shaw, F Singer, PJ Sterk, R Djukanovic, SE Dahlen, YK Guo, KF Chung, E Guttman-Yassky, and IM Adcock, and the U-BIOPRED study group, 2021. Mapping atopic dermatitis and anti-IL-22 response signatures to Type 2-low severe neutrophilic asthma. Journal of Allergy and Clinical Immunology. S0091-6749(21)00648-5.
D Rago, CT Pedersen, M Huang, RS Kelly, G Gurdeniz, N Brustad, H Knihtil, KA Lee-Sarwar, A Morin, MA Rasmussen, J Stokholm, K Bonnelykke, AA Litonjua, CE Wheelock, ST Weiss, J Lasky-Su, H Bisgaard, BL Chawes, 2021. Characteristics and Mechanisms of a Sphingolipid-associated Childhood Asthma Endotype. American Journal of Respiratory and Critical Care Medicine. 203(7):853-863.
AK Johnsson, JH Choi, E Ronnberg, D Fuchs, J Kolmert, M Hamberg, B Dahlen, CE Wheelock, SE Dahlen, and G Nilsson, 2021. Selective inhibition of prostaglandin D2 biosynthesis in human mast cells to overcome need for multiple receptor antagonists: Biochemical consequences. Clinical and Experimental Allergy. 51(4):594-603.
A Mazein, O Ivanova, I Balaur, M Ostaszewski, V Berzhitskaya, T Serebriyskaya, T Ligon, J Hasenauer, B De Meulder, RW Overall, L Roy, RG Knowles, CE Wheelock, SE Dahlen, KF Chung, IM Adcock, G Roberts, R Djukanovic, J Pellet, P Gawron, R Balling, AH Maitland-van der Zee, R Schneider, PJ Sterk, C Auffray, the U-BIOPRED Studu Group, 2021. AsthmaMap: An interactive knowledge repository for mechanisms of asthma. Journal of Allergy and Clinical Immunology. 147(3):853-6.
I Meister, P Zhang, A Sinha, CM Skold, AM Wheelock, T Izumi, R Chaleckis, CE Wheelock, 2021. High-Precision Automated Workflow for Urinary Untargeted Metabolomic Epidemiology. Analytical Chemistry. 93(12):5248-5258.
J Kolmert, C Gómez, D Balgoma, M Sjödin, M Eriksson, M Mikus, J-O Thörngren; AJ James, A Sousa, P Bakke, H Bisgaard, FK Chung, M Caruso, P Chanez, A D’Amico, SJ Fowler, T Geiser, P Howarth, I Horváth, N Krug, P Montuschi, J Musial, T Sandström, DE Shaw, I Pandis, R Knowles, R Djukanovic, B Dahlén, PJ Sterk, SE Dahlén, CE Wheelock, on behalf of the U-BIOPRED Study Group, 2020. Increased urinary leukotriene E4 and prostaglandin D2 metabolites in severe asthma and type-2 inflammation. American Journal of Respiratory and Critical Care Medicine, 203(1):37-53.
NZ Kermani, M Saqi, P Agapow, S Pavlidis, CH Kuo, KS Tan, S Mumby, K Sun, M Loza, F Baribaud, AR Sousa, J Riley, AM Wheelock, CE Wheelock, B De Meulder, J Schofield, S Sanchez-Ovando, JL Simpson, KJ Baines, PA Wark, C Auffray, SE Dahlen, PJ Sterk, R Djukanovic, IM Adcock, YK Guo, KF Chung, the U-BIOPRED Studu Group, 2021. Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics. Allergy. 76(1):380-3.
JM Harder, C Guymer, JPM Wood, E Daskalaki, G Chidlow, C Zhang, R Balasubramanian, BH Cardozo, NE Foxworth, KE Deering, TB Ouellette, C Montgomery, CE Wheelock, RJ Casson, PA Williams, SWM John, 2020. Disturbed glucose and pyruvate metabolism in glaucoma with neuroprotection by pyruvate or rapamycin. Proceedings of the National Academy of Sciences U S A. 117(52):33619-33627.
S Eisinger, D Sarhan, VF Boura, I Ibarlucea-Benitez, S Tyystjärvi, G Oliynyk, M Arsenian-Henriksson, D Lane, SL Wikström, R Kiessling, T Virgilio, SF Gonzalez, D Kaczynska, S Kanatani, E Daskalaki, CE Wheelock, S Sedimbi, BJ Chambers, JV Ravetch, MCI Karlsson, 2020. Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells. Proceedings of the National Academy of Sciences U S A. 2020 Dec 15;117(50):32005-32016
I Tada, R Chaleckis, H Tsugawa, I Meister, P Zhang, N Lazarinis, B Dahlén, CE Wheelock, M Arita, 2020. Correlation-Based Deconvolution (CorrDec) To Generate High-Quality MS2 Spectra from Data-Independent Acquisition in Multisample Studies. Analytical Chemistry. 92(16):11310-11317.
SH Møller, M Mellergaard, M Madsen, AV Bermejo, SD Jepsen, MH Hansen, RI Høgh, BI Aldana, C Desler, LJ Rasmussen, EG Sustarsic, Z Gerhart-Hines, E Daskalaki, CE Wheelock, TK Hiron, D Lin, CA O'Callaghan, HH Wandall, L Andresen, S Skov, 2020. Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells. Frontiers in Immunology. 11:1968.