Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

Years

Publications

M Sjödin, A Checa, M Yang, SE Dahlén, ÅM Wheelock, J Grunewald, CE Wheelock, 2018. Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis. Respiratory Research, 19(1):236.
CX Li, CE Wheelock CE, CM Sköld, ÅM Wheelock, 2018. Integration of multi-omics datasets enables molecular classification of COPD. European Respiratory Journal. 51(5).
B Burla, M Arita, M Arita, AK Bendt, A Cazenave-Gassiot, EA Dennis, K Ekroos, X Han, K Ikeda, G Liebisch, MK Lin, T Ping Loh, PJ Meikle, M Orešič, O Quehenberger, A Shevchenko, F Torta, MJO Wakelam, CE Wheelock, and MR Wenk, 2018. Mass spectrometry-based lipidomics of human blood plasma - a community-initiated position paper aimed at developing generally accepted guidelines. 59(10):2001-2017.
A Mazein, RG Knowles, I Adcock, KF Chung, CE Wheelock, AH Maitland-van der Zee, PJ Sterk, C Auffray, 2018. AsthmaMap: An expert-driven computational representation of disease mechanisms; AsthmaMap Project Team. Clinical Experimental Allergy. 48(8):916-918.
M Dyszynski, M Vesterlund, AC Björklund, V Zachardias, J Janssen, H Gallart-Ayala, CE Wheelock, J Lehtiö, D Grandér, K Pokrovskaja Tamm, R Nilsson, 2018. Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment. Cell Death and Disease, 9(9):846.
A Mahdi, O Kövamees, A Checa, CE Wheelock, M von Heijne, M Alvarsson, J Pernow, 2018. Arginase inhibition improves endothelial function in patients with type 2 diabetes mellitus despite intensive glucose lowering therapy. Journal of Internal Medicine. 284(4):388-398.
SN Reinke, B Galindo-Prieto, T Skotare, DI Broadhurst, A Singhania, D Horowitz, R Djukanović, TSC Hinks, P Geladi, J Trygg, CE Wheelock, 2018. OnPLS-based multi-block data integration: a multivariate approach to interrogating biological interactions in asthma. Analytical Chemistry, in press.
J Kolmert, A Fauland, D Fuchs, J Säfholm, C Gomez, M Adner, SE Dahlén, CE Wheelock, 2018. Lipid mediator quantification in isolated human and guinea pig airways – an expanded approach for respiratory research. Analytical Chemistry, 90(17):10239-10248.
D Fuchs, M Hamberg, CM Sköld, ÅM Wheelock, CE Wheelock, 2018. An LC-MS/MS workflow to characterize 16 regio- and stereoisomeric trihydroxyoctadecenoic acids (TriHOMEs). Journal Lipid Research. pii: jlr.D087429.
R Chaleckis, I Meister, P Zhang, CE Wheelock, 2018. Challenges, progress and promises of metabolite annotation for LC–MS-based metabolomics. Current Opinion in Biotechnology, edited by Saulius Klimasauskas and Linas Mazutis. 55:44-50.
E Daskalaki, NJ Pillon, A Krook, CE Wheelock, A Checa, 2018. The influence of culture media upon observed cell secretome metabolite profiles: the balance between cell viability and data interpretability. Analytica Chimica Acta, 1037:338-350.
A Laguna-Fernández, A Checa, M Carracedo, G Artiach, MH Petri, M Josefa Forteza, X Jiang, R Baumgartner, T Andonova, H Arnardottir, A Gisterå, S Thul, CE Wheelock, G Paulsson-Berne, D Ketelhuth, GK Hansson, M Bäck, 2018. CHEMR23 signaling protects from atherosclerosis by modifying oxLDL uptake and phagocytosis in macrophages. Circulation, in press. doi: 10.1161/CIRCULATIONAHA.117.032801
R Chaleckis, S Naz, I Meister, CE Wheelock, 2018. LC-MS based metabolomics of biofluids using all ion fragmentation (AIF) acquisition. Methods in Molecular Biology. Ed. Martin Giera. Springer Nature, 1730:45-58.