Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

Years

Publications

SN Reinke, B Galindo-Prieto, T Skotare, DI Broadhurst, A Singhania, D Horowitz, R Djukanović, TSC Hinks, P Geladi, J Trygg, CE Wheelock, 2018. OnPLS-based multi-block data integration: a multivariate approach to interrogating biological interactions in asthma. Analytical Chemistry, in press.
D Fuchs, M Hamberg, CM Sköld, ÅM Wheelock, CE Wheelock, 2018. An LC-MS/MS workflow to characterize 16 regio- and stereoisomeric trihydroxyoctadecenoic acids (TriHOMEs). Journal Lipid Research. pii: jlr.D087429.
J Kolmert, A Fauland, D Fuchs, J Säfholm, C Gomez, M Adner, SE Dahlén, CE Wheelock, 2018. Lipid mediator quantification in isolated human and guinea pig airways – an expanded approach for respiratory research. Analytical Chemistry, 90(17):10239-10248.
R Chaleckis, I Meister, P Zhang, CE Wheelock, 2018. Challenges, progress and promises of metabolite annotation for LC–MS-based metabolomics. Current Opinion in Biotechnology, edited by Saulius Klimasauskas and Linas Mazutis. 55:44-50.
E Daskalaki, NJ Pillon, A Krook, CE Wheelock, A Checa, 2018. The influence of culture media upon observed cell secretome metabolite profiles: the balance between cell viability and data interpretability. Analytica Chimica Acta, 1037:338-350.
A Checa, A Malmqvist, L Flyckt, L Schwieler, M Samuelsson, E Skogh, S Cervenka, ML Dahl, F Piehl, Karolinska Schizophrenia Project (KaSP) consortium, S Erhardt, CE Wheelock, 2018. Intrathecal sphingolipids associate with disease severity in first episode psychosis patients. Schizophrenia Research, 199:438-441.
R Emma, AT Bansal, J Kolmert, CE Wheelock, SE Dahlén, MJ Loza, B De Meulder, D Lefaudeux, C Auffray, B Dahlén, PS Bakke, P Chanez, I Horvath, A Chaiboonchoe, H Ahmed, S Ballereau, C Rossios, KF Chung, P Montuschi, SJ Fowler, IM Adcock, AD Postle, A Rowe, PJ Sterk, R Djukanovic; the U-BIOPRED Study Group, 2018. Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort. PLoS One, 13(9):e0203874.
E Garreta-Lara, A Checa, D Fuchs, R Tauler, S Lacorte, CE Wheelock, C Barata, 2018. Effect of psychiatric drugs on Daphnia magna oxylipin profiles. Science of the Total Environment. 644:1101–1109.
AC Araujo, CE Wheelock, JZ Haeggström, 2018. The eicosanoids, redox regulated lipid mediators in immunometabolic disorders. Antioxidants and Redox Signaling. 29(3):275-296.
A Laguna-Fernández, A Checa, M Carracedo, G Artiach, MH Petri, M Josefa Forteza, X Jiang, R Baumgartner, T Andonova, H Arnardottir, A Gisterå, S Thul, CE Wheelock, G Paulsson-Berne, D Ketelhuth, GK Hansson, M Bäck, 2018. CHEMR23 signaling protects from atherosclerosis by modifying oxLDL uptake and phagocytosis in macrophages. Circulation, in press. doi: 10.1161/CIRCULATIONAHA.117.032801
R Chaleckis, S Naz, I Meister, CE Wheelock, 2018. LC-MS based metabolomics of biofluids using all ion fragmentation (AIF) acquisition. Methods in Molecular Biology. Ed. Martin Giera. Springer Nature, 1730:45-58.
J Kolmert, S Piñeiro Hermida, JA Gregory, IP López, A Fauland, CE Wheelock, SE Dahlén, JM García Pichel, M Adner, 2018. Prominent release of lipoxygenase generated mediators in a murine house dust mite-induced asthma model. Prostaglandins and Other Lipid Mediators, 137:20-29.
A Al-Mashhadi, A Checa, N Wåhlin, T Neveus, M Fossum, CE Wheelock, B Karanikas, A Stenberg, AEG Persson, M Carlström, 2018. Changes in arterial pressure and markers of nitric oxide homeostasis and oxidative stress following surgical correction of hydronephrosis in children. Pediatric Nephrology. 33(4):639-649.
MA Kamleh, O McLeod, A Checa, D Baldassarre, F Veglia, K Gertow, SE Humphries, R Rauramaa, U de Faire, AJ Smit, P Giral, S Kurl, E Mannarino and E Tremoli, on behalf of the IMPROVE study group, A Silveira, J Örvik, A Hamsten, and CE Wheelock, 2018. Increased levels of circulating fatty acids are associated with protective effects against future cardiovascular events in non-diabetics. Journal of Proteome Research, 17(2):870-878.
LA García-Flores, S Medina, C Gómez, CE Wheelock, R Cejuela, JM Martínez-Sanz, C Oger, JM Galano, T Durand, Á Hernández-Sáez, F Ferreres, Á Gil-Izquierdo, 2018. Aronia-citrus juice (polyphenol-rich juice) intake and elite triathlon training: a lipidomic approach using representative oxylipins in urine. Food and Function. 9(1):463-475.
C Wefers, T Duiveman-de Boer, P LM Zusterzeel, L FAG Massuger, D Fuchs, R Torensma, CE Wheelock, I. JM. de Vries, 2018. Different Lipid Regulation in Ovarian Cancer: The Influence on the Immune System. International Journal of Molecular Sciences, 19(1).
J Hartler, A Triebl, A Ziegl, M Trötzmüller, GN Rechberger, OA Zeleznik, KA Zierler, F Torta, A Cazenave-Gassiot, MR Wenk, A Fauland, CE Wheelock, AM Armando, O Quehenberger, Q Zhang, MJO Wakelam, G Haemmerle, F Spener, HC Köfeler, GG Thallinger, 2017. Deciphering lipid structures based on platform-independent decision rules. Nature Methods. 14(12):1171-1174.
JA Bowden, A Heckert, CZ Ulmer, CM Jones, JP Koelmel, L Abdullah, L Ahonen, Y Alnouti, A Armando, JM Asara, T Bamba, JR Barr, J Bergquist, CH Borchers, J Brandsma, SB Breitkopf, T Cajka, A Cazenave-Gassiot, A Checa, MA Cinel, RA Colas, S Cremers, EA Dennis, JE Evans, A Fauland, O Fiehn, MS Gardner, TJ Garrett, KH Gotlinger, J Han, Y Huang, AH Neo, T Hyotylainen, Y Izumi, H Jiang, H Jiang, J Jiang, M Kachman, R Kiyonami, K Klavins, C Klose, HC Kofeler, J Kolmert, T Koal, G Koster, Z Kuklenyik, IJ Kurland, M Leadley, K Lin, KR Maddipati, D McDougall, PJ Meikle, NA Mellett, C Monnin, MA Moseley, R Nandakumar, M Oresic, RE Patterson, D Peake, JS Pierce, M Post, AD Postle, R Pugh, Y Qui, O Quehenberger, P Ramrup, J Rees, B Rembiesa, D Reynaud, MR Roth, S Sales, K Schuhmann, ML Schwartzman, CN Serhan, A Shevchenko, SE Somerville, LS John-Williams, MA Surma, H Takeda, R Thakare, JW Thompson, F Torta, A Triebl, M Trotzmuller, SJK Ubhayasekera, D Vuckovic, JM Weir, R Welti, MR Wenk, CE Wheelock, L Yao, M Yuan, XH Zhao, S Zhou, 2017. Harmonizing Lipidomics: NIST Interlaboratory Comparison Exercise for Lipidomics using Standard Reference Material 1950 Metabolites in Frozen Human Plasma. Journal of Lipid Research. 58(12):2275-2288.
M Peleli, P Flacker, Z Zhuge, C Gomez, CE Wheelock, AEG Persson, M Carlstrom, 2017. Renal denervation attenuates hypertension and renal dysfunction in a model of cardiovascular and renal disease, which is associated with reduced NADPH and xanthine oxidase activity. Redox Biology 13:522-527.
Checa, H Idborg, A Zandian, DG Sar, I Surowiec, J Trygg, E Svenungsson, PJ Jakobsson, P Nilsson, I Gunnarson, and CE Wheelock, 2017. Dysregulations in circulating sphingolipids associate with disease activity indices in female patients with systemic lupus erythematous: a cross-sectional study. Lupus, 26(10):1023-1033.

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