Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

Years

Publications

M Hezel, M Peleli, M Liu, C Zollbrecht, BL Jensen, A Checa, A Giulietti, CE Wheelock, JO Lundberg, E Weitzberg and M Carlström, 2016. Dietary nitrate improves age-related hypertension and metabolic abnormalities via modulation of angiotensin II receptor signaling and inhibition of superoxide generation. Free Radical and Biology Medicine. 26(99):87-98.
D Paquin-Proulx, A Gibbs, S Bächle, A Checa, A Introini, E Leeansyah, CE Wheelock, DF Nixon, K Broliden, A Tjernlund, M Moll, and JK Sandberg, 2016. Innate iNKT cell recognition of HIV-1 infected dendritic cells is an early detection mechanism targeted by viral immune evasion. Journal of Immunology. 197(5):1843-51.
T Yang, C Zollbrecht, ME Winerdal, Z Zhuge, XM Zhang, N Terrando, A Checa, J Sällström, CE Wheelock, O Winqvist, RA Harris, E Larsson, AE Persson, BB Fredholm, M Carlström, 2016. Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension. Journal of the American Heart Association, 18;5(7). pii: e003868.
M Carlström, C Cananau, A Checa, K Wide, L Sartz, A Svensson, CE Wheelock, S Westphal, Z Békássy, P Bárány, JO Lundberg, S Hansson, E Weitzberg, RT Krmar, 2016. Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia. Nitric Oxide, 58:1-9.
D Balgoma, M Yang, M Sjödin, SG Snowden, R Karimi, B Levänen, H Merikallio, R Kaarteenaho, L Palmberg, K Larsson, DJ Erle, SE Dahlén, B Dahlén, CM Sköld, ÅM Wheelock, and CE Wheelock, 2016. Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD. European Respiratory Journal, 47(6):1645-56.
K Jandl, E Stacher, Z Bálint, EM Sturm, J Maric, M Peinhaupt, P Luschnig, I Aringer, A Fauland, V Konya, SE Dahlen, CE Wheelock, D Kratky, A Olschewski, G Marsche, R Schuligoi, A Heinemann, 2016. Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung. J Allergy Clin Immunol. 137(3):833-43.
RB Frei, P Luschnig, GP Parzmair, M Peinhaupt, S Schranz, A Fauland, CE Wheelock, A Heinemann, EM Sturm, 2016. Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen-induced pulmonary inflammation in mice. Allergy. Feb 6. doi: 10.1111/all.12858.
I Roci, H Gallart-Ayala, A Schmidt, J Watrous, M Jain, CE Wheelock, R Nilsson, 2016. Metabolite profiling and stable isotope tracing in sorted subpopulations of mammalian cells. Analytical Chemistry. 88(5):2707-13.
L Perisic, S Aldi, Y Sun, L Folkersen, A Razuvaev, J Roy, M Lengquist, S Åkesson, CE Wheelock, L Maegdefessel, A Gabrielsen, J Odeberg, G Hansson, G Paulsson-Berne, U Hedin, 2016. Gene expression signatures, pathways and networks in carotid atherosclerosis. Journal of Internal Medicine, 279(3):293-308.
A Checa, T Holm, MOD Sjödin, SN Reinke, J Alm, A Scheynius, CE Wheelock, 2015. Lipid mediator profile in vernix caseosa reflects skin barrier development. Scientific Reports 5:15740 | DOI:10.1038/srep15740.
ML Oliveira, FL D'Alexandri, G Pugliesi, V Van Hoeck, FS Mesquita, CM Membrive, JA Negrão, CE Wheelock, M Binelli, 2015. Peri-ovulatory endocrine regulation of the prostanoid pathways in the bovine uterus at early dioestrus. Reproduction Fertility and Development Oct 14. doi: 10.1071/RD15269.
A Checa, N Xu, DG Sar, JZ Haeggström, M Ståhle, CE Wheelock, 2015. Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment. Scientific Reports. 5:12017 | DOI: 10.1038/srep12017.
JR Bood, BM Sundblad, I Delin, M Sjödin, KS Larsson, SD Anderson, CE Wheelock, SE Dahlen, B Dahlen, 2015. Urinary excretion of lipid mediators in response to repeated eucapnic voluntary hyperpnea in asthmatics. Journal of Applied Physiology. In press. doi: 10.1152/japplphysiol.00301.2015
MP Hezel, M Liu, TA Schiffer, FJ Larsen, A Checa, CE Wheelock, M Carlström, JO Lundberg, E Weitzberg, 2015. Effects of long-term dietary nitrate supplementation in mice. Redox Biology. 29(5):234-242.
MA Kamleh, SG Snowden, G Blackburn, DG Watson, N Xu, M Ståhle, and CE Wheelock, 2015. LC-MS metabolomics of psoriasis patients reveals disease severity-dependent increases in circulating amino acids that are ameliorated by anti-TNFα treatment. Journal of Proteome Research, 14:557-566.
JD Brannan, J Bood, A Alkhabaz, D Balgoma, J Otis, I Delin, B Dahlén, CE Wheelock, P Nair, SE Dahlén, PM O'Byrne, 2015. The effect of omega-3 fatty acids on bronchial hyperresponsiveness, sputum eosinophilia and mast cell mediators in asthma. Chest, 147(2):397-405.
Hexosylceramides as intrathecal markers of worsening disability in multiple sclerosis. Checa A, Khademi M, Sar DG, Haeggström JZ, Lundberg JO, Piehl F, Olsson T, Wheelock CE. Mult Scler. 2014 Dec 5. pii: 1352458514561908.
S Snowden, D Grapov, M Settergren, FL D’Alexandri, T Pedersen, JZ Haeggström, JW Newman, O Fiehn, T Hyötyläinen, M Orešič, J Pernow, CE Wheelock, 2014. High dose simvastatin exhibits enhanced lipid lowering effects relative to simvastatin/ezetimibe combination therapy. Circulation: Cardiovascular Genetics, 7(6):955-64.
D Diez, A Agusti, and CE Wheelock, 2014. Network analysis in the investigation of chronic respiratory diseases: from basics to application. American Journal of Respiratory and Critical Care Medicine, 190(9):981-8.
LC van den Berk, BJ Jansen, S Snowden, KG Siebers-Vermeulen, C Gilissen, G Kögler, CG Figdor, CE Wheelock, R Torensma, 2014. Cord blood mesenchymal stem cells suppress DC-T cell proliferation via prostaglandinB2. Stem Cells and Development, 23(14):1582-93.

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