Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

Years

Publications

K Daham, A James, D Balgoma, M Kupczyk, B Billing, A Lindeberg, E Henriksson, GA Fitzgerald, CE Wheelock, SE Dahlén, B Dahlén, 2014. Effects of selective COX-2 inhibition on allergen-induced bronchoconstriction and airway inflammation in asthma. Journal of Allergy and Clinical Immunology, 134(2):306-13.
FJ Larsen, TA Schiffer, B Ekblom, MP Mattsson, A Checa, CE Wheelock, T Nyström, JO Lundberg, E Weitzberg. Dietary nitrate reduces resting metabolic rate: a randomized, crossover study in humans, 2014. American Journal of Clinical Nutrition, 99(4):843-50.
N Larsson, SL Lundström, R Pinto, G Rankin, M Karimpour, A Blomberg, T Sandström, J Pourazar, J Trygg, AF Behndig, CE Wheelock*, and ML Nording, 2014. Lipid mediator profiles differ between lung compartments in asthmatic and healthy humans. European Respiratory Journal, 43(2):453-63.
Wheelock CE, Goss VM, Balgoma D, Nicholas B, Brandsma J, Skipp PJ, Snowden S, Burg D, D'Amico A, Horvath I, Chaiboonchoe A, Ahmed H, Ballereau S, Rossios C, Chung KF, Montuschi P, Fowler SJ, Adcock IM, Postle AD, Dahlén SE, Rowe A, Sterk PJ, Auffray C, Djukanovic R; the U-BIOPRED Study Group, 2013. Application of 'omics technologies to biomarker discovery in inflammatory lung diseases. European Respiratory Journal 42(3):802-25.
Wheelock ÅM, Wheelock CE, 2013. Trials and tribulations of 'omics data analysis: assessing quality of SIMCA-based multivariate models using examples from pulmonary medicine. Molecular Biosystems 9(11):2589-96.
D Balgoma, A Checa, DG Sar, S Snowden, and CE Wheelock, 2013. Metabolic profiling of lipid mediators in disease. Molecular Nutrition and Food Research, 57(8):1359-77.
SL Lundström, J Yang, JD Brannan, JZ Haeggström, BD Hammock, P Nair, P O’Byrne, SE Dahlén, and CE Wheelock, 2013. Lipid mediator serum profiles in asthmatics significantly shift following dietary supplementation with omega-3 fatty acids. Molecular Nutrition and Food Research, 57(8):1378-89.
SL Lundström, R Saluja, M Adner, JZ Haeggström, G Nilsson, and CE Wheelock, 2013. Lipid mediator metabolic profiling demonstrates differences in eicosanoid patterns in two phenotypically distinct mast cell populations. Journal Lipid Research. 54(1):116-26.
A Nasi, T Fekete, A Krishnamurthy, S Snowden, E Rajnavölgyi, AI Catrina, CE Wheelock, N Vivar, B Rethi. Dendritic cell reprogramming by endogenously produced lactic acid, 2013. Journal of Immunology. 191(6):3090-9.
D Balgoma, J Larsson, J Rokach, JA Lawson, K Daham, B Dahlén, SE Dahlén, CE Wheelock. Quantification of Lipid Mediator Metabolites in Human Urine from Asthma Patients by Electrospray Ionization Mass Spectrometry: Controlling Matrix Effects. Analytical Chemistry, 85(16):7866-74.
A Nasi, T Fekete, A Krishnamurthy, S Snowden, E Rajnavölgyi, AI Catrina, CE Wheelock, N Vivar, B Rethi. Dendritic cell reprogramming by endogenously produced lactic acid, 2013. Journal of Immunology. 191(6):3090-9.
GM Kirwan, E Johansson, R Kleemann, ER Verheij, ÅM Wheelock, S Goto, J Trygg, and CE Wheelock, 2012. Building multivariate systems biology models. Analytical Chemistry 84(16):7064-71.
S Snowden, SE Dahlén, and CE Wheelock, 2012. Application of metabolomics approaches to the study of respiratory diseases. Bioanalysis special issue on “Metabolomics”, Guest Editor Andy Nicholls, 4(18):2265-90.
SL Lundström, J Yang, HJ Källberg, S Thunberg, G Gafvelin, JZ Haeggström, R Grönneberg, J Grunewald, M van Hage, BD Hammock, A Eklund, ÅM Wheelock, and CE Wheelock, 2012. Allergic asthmatics show divergent lipid mediator profiles from healthy controls both at baseline and following birch pollen provocation. PLoS ONE 7(3):e33780.
D Diez, S Goto, JV Fahy, DJ Erle, PG Woodruff, ÅM Wheelock, and CE Wheelock, 2012. Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics. BMC Medical Genomics, 5:27.
SL Lundström, D Balgoma, ÅM Wheelock, JZ Haeggström, SE Dahlén, and CE Wheelock, 2010. Lipid Mediator Profiling in Pulmonary Disease. Current Pharmaceutical Biotechnology special issue on "Frontiers of Metabolomics: Going from Bench to Bed Side". 12(7):1026-1052.
SL Lundström, B Levänen, M Nording, A Klepczynska-Nyström, M Sköld, JZ Haeggström , J Grunewald, M Svartengren, BD Hammock, BM Larsson, A Eklund, ÅM Wheelock, and CE Wheelock, 2011. Asthmatics exhibit altered oxylipin profiles compared to healthy individuals after subway air exposure. PLoS One 6(8):e23864.
K Gertow, E Nobili, L Folkersen, J Newman, T Pedersen, J Ekstrand, J Swedenborg, H Kühn, CE Wheelock, GK Hansson, U Hedin, JZ Haeggström, and A Gabrielsen, 2011. Expression of 12- and 15-lipoxygenase mRNAs in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms. Atherosclerosis 215(2):411-416.
SL Lundström, B Levänen, M Nording, A Klepczynska-Nyström, M Sköld, JZ Haeggström , J Grunewald, M Svartengren, BD Hammock, BM Larsson, A Eklund, ÅM Wheelock, and CE Wheelock, 2011. Asthmatics exhibit altered oxylipin profiles compared to healthy individuals after subway air exposure. PLoS One 6(8):e23864.
GM Kirwan, D Diez, JZ Haeggström, S Goto, and CE Wheelock, 2010. Systems biology approaches for investigating the relationship between lipids and cardiovascular disease. Current Cardiovascular Risk Reports 5:52-61.

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