Integrative Molecular Phenotyping
INTEGRATIVE MOLECULAR
PHENOTYPING
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY
DEPARTMENT OF MEDICAL
BIOCHEMISTRY AND BIOPHYSICS
WHEELOCK LABORATORY

Years

Publications

MP Endsley, MA Isbell, L Cui, CE Wheelock, BD Hammock, JR Falck, WB Campbell, and K Nithipatikom, 2007. Effects of exogenous 2-arachidonoylglycerol hydrolysis and 12-lipoxygenase on prostate carcinoma (PC-3) cell invasion. International Journal of Cancer 121(5):984-991.
T Kadowaki, CE Wheelock, T Adachi, T Kudo, S Okamoto, N Tanaka, K Tonomura, G Tsujimoto, H Mamitsuka, S Goto, and M Kanehisa, 2007. Identification of endocrine disruptor biodegradation by integration of structure-activity relationship with pathway analysis. Environ Science and Technology 41:7997-8003.
J Normark, D Nilsson, U Ribacke, G Winter, K Moll, CE Wheelock, J Bayarugaba, F Kironde, TG Egwang, Q Chen, B Andersson, and M Wahlgren, 2007. PfEMP1 motifs predict severity of Plasmodium falciparum malaria. PNAS 104(40):15835-15840.
RM Wadkins, JL Hyatt, CC Edwards, L Tsurkan, MR Redinbo, CE Wheelock, PD Jones, BD Hammock, and PM Potter, 2007. QSAR analysis of trifluoromethylketone-mediated inhibition of mammalian carboxylesterases. Molecular Pharmacology 71(3):713-723.
CE Wheelock, S Goto, BD Hammock, and JW Newman, 2007. Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice. Metabolomics 3(2):137-145.
CJ Hillard, W-S V Ho, J Thompson, K M Gauthier, CE Wheelock, H Huang and BD Hammock, 2007. Effects of catabolic inhibitors on vasodilation of rat middle cerebral artery by the endocannabinoid, 2-arachidonylglycerol. British Journal Pharmacology 152(5):691-698.
CN Hayes, AM Wheelock, J Normark, MC Wahlgren, S Goto, and CE Wheelock, 2006. Enlistment of omics technologies in the fight against malaria: Panacea or Pandora’s box? Journal of Pesticide Science 31(3):263-272.
CE Wheelock, Y Nakagawa, T Harada, N Oikawa, M Akamatsu, G Smagghe, D Stefanou, K Iatrou, and L Swevers, 2006. High-throughput screening of ecdysone agonists using a reporter gene assay followed by 3-D QSAR analysis of the molting hormonal activity. Bioorganic and Medicinal Chemistry 14(4):1143-1159.
CE Wheelock, JL Miller, MJ Miller, BM Phillips, SA Huntley, SJ Gee, RS Tjeerdema, and BD Hammock, 2006. Evaluation of esterase activity for use in removal of pyrethroid-associated toxicity to Ceriodaphnia dubia and Hyalella azteca. Environmental Toxicology and Chemistry 25(4):973-984.
T Kadowaki, CE Wheelock, M Hattori, S Goto, and M Kanehisa, 2006. Structure-activity relationships and pathway analysis of biological degradation processes. Journal of Pesticide Science 31(3):273-281.
CE Wheelock and H Miyagawa, 2006. Editorial: The omicsization of agriculture. Journal of Pesticide Science 31(3):240-244.
M Wogulis, CE Wheelock, SG Kamita, AC Hinton, PA Whetstone, BD Hammock, and DK Wilson, 2006. Structural studies of a potent insect maturation inhibitor bound to the juvenile hormone esterase of Manduca sexta. Biochemistry 45(13):4045-4057.
K Kang, PD Jones, H Huang, R Zhang, LA Mostovich, CE Wheelock, T Watanabe, LF Gulyaeva, and BD Hammock, 2005. Evaluation of -cyanoethers as fluorescent substrates for assay of cytochrome P450 enzyme activity. Analytical Biochemistry 344(2):183-192.
K. Nithipatikom, MP Endsley, MA Isbell, CE Wheelock, BD Hammock, and WB Campbell, 2005. A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells. Biochemical and Biophysical Research Communications 332(4):1028-1033.
CE Wheelock, K Eder, I Werner, H Huang, PD Jones, BF Brammell, AA Elskus, and BD Hammock, 2005. Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos. Aquatic Toxicology 74(2):172-192.
CE Wheelock, JL Miller, MJ Miller, BM Phillips, SJ Gee, RS Tjeerdema, and BD Hammock, 2005. Influence of container adsorption upon observed pyrethroid toxicity to Ceriodaphnia dubia and Hyalella azteca. Aquatic Toxicology 74(1):47-52.
CE Wheelock, G Shan, J Ottea, 2005. Overview of carboxylesterases and their role in the metabolism of insecticides. Journal of Pesticide Science 30(2):75-83.
CE Wheelock, JL Miller, SJ Gee, G Shan, and BD Hammock, 2004. Development of Toxicity Identification Evaluation (TIE) procedures for pyrethroid detection using esterase activity. Environmental Toxicology and Chemistry 23(11):2699–2708.
JE Stok, H Huang, PD Jones, CE Wheelock, C Morisseau, and BD Hammock, 2004. Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes. Journal of Biological Chemistry 279(28):29863-29869.
RD McAbee, KD Kang, MA Stanich, J Christiansen, CE Wheelock, A Inman, BD Hammock, and AJ Cornel, 2004. Pyrethroid tolerance in Culex pipiens molestus var molestus from Marin County, California. Pest Management Science 60:359-368.

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